2007—2009年我院抗真菌药应用分析

目的分析我院抗真菌药的用药现状及趋势,为临床合理使用抗真菌药提供参考。方法通过医院信息管理系统,对我院2007—2009年抗真菌药的销售金额和数量进行统计分析,并计算用药频率(DDDs)及药品日均费用(DDC)。结果 2007—2009年使用的抗真菌药销售金额年均增长速度为23.70%,3年吡咯类抗真菌药销售金额均列第1位,棘白菌素类抗真菌药销售金额年均增长速度为92.3%。2007—2009年我院抗真菌药的使用金额占各年抗菌药物销售金额的比例分别为13.7%、12.3%及11.0%。注射剂的使用金额(1 255.13万元)高于口服制剂(187.40万元)。伊曲康唑3年中销售金额(652.03万元)、DDDs(27 026～34 200)均排在第1位,销售金额占所有抗真菌药的38.7%,但DDC仅为17.8～18.8元/d。结论我院抗真菌药临床应用较合理,伊曲康唑是临床使用最广泛的抗真菌药。部分品种存在不合理使用现象,需加强监管。

Analysis of the Utilization of Antifungal Agents in Our Hospital during 2007-2009

Objective To analyze the utilization and trend of antifungal agents during 2007—2009 in our hospital in order to provide references for clinical drug use.Methods The antifungal agents used in our hospital from 2007 to 2009 were analyzed statistically in terms of drug consumption sum,sales amount,DDDs and DDC through hospital information management system.Results The sales amount of antifungal drugs had grown at an average annual rate of 23.70% from 2007 to 2009.The sales amount of pyrrole antifungal drugs was in the first place during the three years.The sales amount of echinocandin antifungal drugs had grown at an average annual rate of 92.3%.The consumption sum of antifungal agents accounted for 13.7%,12.3%,11.0% of the sales amount of all the antibiotics from 2007—2009.The consumption sum of injections(12.5513 million yuan) was higher than oral agents(1.874 million yuan).DDDs(27 026~34 200) and sales amount of Itraconazole were both in the first place over the three years,and its sales amount(6.5203 million yuan) accounted for 38.7% of the antifungal drugs,but DDC was just 17.8~18.8 yuan/d.Conclusion The use of the antifungal agents in our hospital is reasonable.However,some categories of drugs are used irrationally,thus monitoring of their clinical use should be intensified.