颈内动脉狭窄或闭塞经颅多普勒超声、脑血流灌注及磁共振血管造影对比研究

目的 应用经颅多普勒超声（TCD）、脑血流灌注（SPECT）及磁共振血管造影（MRA）检查，探讨对颈内动脉（ICA）狭窄或闭塞的早期诊断价值。方法42例ICA狭窄或闭塞患者经TCD、SPECT及MRA检查，与DSA进行对比分析。结果TCD、MRA对ICA狭窄或闭塞检测结果与DSA比较，符合率分别为90、8％、80．5％，对侧枝循环开放判断，符合率分别为92．2％、47、6%。TCD检测患侧和健侧MCA的Vs、PI值存在显著性差异（P〈0.001）。SPECT阳性区与MCA的Vm、PI相关系数分别为-0、672，-0．658，有良好的相关性。结论TCD、SPECT及MRA检查联合应用，从不同角度为ICA狭窄或闭塞的早期诊断提供了较全面的客观依据，是可靠的综合性检查方法。

Comparative Study of Transcranial Doppler, Brain Perfusion Imaging and Magnetic Resonance Angiogrophy in Patients with Internal Carotid Artery Stenosis and Occlusion

Objective Using TCD,SPECT and MRA to de tect internal carotid artery(ICA) stenosis or occlusion and to investigate the d iagnostic value. Methods The results of TCD,SPECT,MRA and DSA were compare d in 42 patients with ICA stenosis and occlusion. Results The coincident rates of TCD and MRA compared with DSA in ICA stenosis and occlusion were 90.8% and 80.5% respectively.In colla teral circulation the coincidendt rates of TCD and MRA compared with DSA were 92 .2% and 47.6% respectively.The Vm and PI in the stenontic side and healthy si de of MCA measured by TCD were significantly different (all<0.0001).The SPECT positive area correlated well with Vm and PI of MCA in TCD (r=-0.672,r =-0.658) respectively. Conclusions TCD,SPECT and MRA may Provide different basis for early diagnosis of ICA stenosis or occlusion.This is the reliable comprehe nsive examination method.