| 进展期胃癌的腹腔缓释化疗 |
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| 引用本文： | 梁寒. 进展期胃癌的腹腔缓释化疗[J]. 中华胃肠外科杂志, 2012, 15(2): 116-117 |
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| 作者姓名： | 梁寒 |
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| 作者单位： | 300060,天津医科大学附属肿瘤医院胃部肿瘤科天津市肿瘤防治重点实验室 |
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| 摘 要： | 由于胃癌标准根治术的确立,局部淋巴结转移已非胃癌复发的主要原因,而腹膜复发转移已成为临床的最主要问题.胃癌腹膜转移的治疗主要为手术加全身治疗及腹腔内治疗.腹腔化疗分为单纯腹腔置药化疗、腹腔热灌注化疗及采取缓释剂的控释化疗.腹腔单纯置药化疗的药代动力学优势不明显;缓释化疗具有药代动力学优势,是预防和治疗胃肠肿瘤腹膜转移的有效方法.
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| 关 键 词： | 胃肿瘤,进展期 腹膜转移 腹腔化疗 |
Intraperitoneal slow released chemotherapy for advanced gastric cancer |
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| LIANG Han. Intraperitoneal slow released chemotherapy for advanced gastric cancer[J]. Chinese journal of gastrointestinal surgery, 2012, 15(2): 116-117 |
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| Authors: | LIANG Han |
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| Affiliation: | Department of Gastrointestinal Cancer, Hospital of Tianjin Medical University, Tianjin, China. tjlianghan@126.com |
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| Abstract: | Regional lymph node recurrence is no longer the prominent concern regarding the prognosis of gastric cancer patients since the establishment of the standard D2 dissection procedure. Peritoneal metastasis has become the most prominent clinical problem. The treatment strategy for peritoneal metastasis includes intraperitoneal chemotherapy,hyperthermic intraperitoneal chemotherapy and intraperitoneal chemotherapy with durg delivery systems. Intraperitoneal chemotherapy has pharmacokinetic advantage when used in combination with drug delivery systems. Intraperitoneal chemotherapy with drug delivery systems is an effective treatment and prevention method. |
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| Keywords: | Stomach neoplasms,advanced Peritoneal metastasis Intraperitoneal chemotherapy |
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