5%杀螺胺乙醇胺盐颗粒剂的制备及其杀螺效果

目的 目的 探讨5%杀螺胺乙醇胺盐颗粒剂的制备方法及其杀螺效果。 方法 方法 通过对润湿剂、 分散剂、 黏合剂和载体 进行筛选， 得出5%杀螺胺乙醇胺盐颗粒剂的最佳配方。将制得的氯硝柳胺乙醇胺盐颗粒剂进行堆密度、 松密度、 水分和热 储稳定性评价， 调查5%杀螺胺乙醇胺盐颗粒剂喷撒法的实验室和现场杀螺效果。结果 结果 5%杀螺胺乙醇胺盐颗粒剂的最 佳配方和制备方法为： 5%的杀螺胺乙醇胺盐、 0.2%的十二烷基硫酸钠、 1%的烷基酚聚氧乙烯基醚磺酸盐混合后， 经气流粉 碎机粉碎， 得到粉末； 再与93.7%的石英砂和0.1%的聚乙烯醇水溶液混合均匀， 烘干， 得杀螺胺乙醇胺盐颗粒剂。所制得的 颗粒剂为干燥、 自由流动的黄色颗粒， 无可见外来物和硬块， 粉尘少， 适于机器施药； 堆密度、 松密度和水分分别为1.4、 1.3 g/ml和2.4%， 热储稳定性合格。实验室采用0.5 g/m2 5%杀螺胺乙醇胺盐颗粒剂喷撒7 d后， 或> 1.0 g/m2 剂量喷撒1 d后， 钉 螺死亡率均> 95%； 现场采用0.5 g/m2 5%杀螺胺乙醇胺盐颗粒剂喷撒7 d后， 或> 1.0 g/m2 剂量喷撒1 d后， 钉螺死亡率均> 85%。 结论 结论 5%杀螺胺乙醇胺盐颗粒剂杀螺效果较好， 是一种适合现场应用的新型杀螺剂型。

Preparation and molluscicidal effect of 5% niclosamide ethanolamine granules

Objective To explore the preparation of 5% niclosamide ethanolamine granules and evaluate its molluscicidal ef- fect. Methods The optimal formula was obtained by the selection of wetting agents, dispersants, adhesives and carriers. The mol- luscieidal effect of 5% nielosamide ethanolamine granules was measured by the spray methods in the laboratory and field. Re- suits The mixed 5% niclosamide ethanolamine, 0.2% sodium lauryl sulfate, and 1% alkylphenol sulfonie polyxyethylene ether sulfonate were crushed by gas flow, and then mixed with 93.7% quartz sand and 0.1% polyvinyl alcohol water solution, drying to 5% niclosamide ethanolamine granules. The density, bulk density, and moisture of 5% niclosamide ethanolamine granules were 1.4 g/ml, 1.3 g/ml, and 2.4%, respectively, and the hot storage stability was qualified. Under the lab condition, the death rates of Oncomelania hupensis snails sprayed with 0.5 g/m2 （7 d） or 1.0 g/m2 （1 d） of 5% niclosamide ethanolamine granules were higher than 95%. In the field, the death rates of the snails sprayed with 0.5 g/m2 （7 d） or 1.0 g/m2 （1 d） were higher than 85%. Conclu- sion There is a high molluseicidal effect of 5% niclosamide ethanolamine granules and it is suitable for field application.