| 重症急性胰腺炎相关脑功能障碍的脱髓鞘病变 |
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| 引用本文： | 韩天权,冯飞灵,张圣道. 重症急性胰腺炎相关脑功能障碍的脱髓鞘病变[J]. 中华肝胆外科杂志, 2010, 16(1). DOI: 10.3760/cma.j.issn.1007-8118.2010.01.027 |
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| 作者姓名： | 韩天权 冯飞灵 张圣道 |
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| 作者单位： | 1. 上海消化外科研究所,上海交通大学医学院附属瑞金医院外科,200025
2. 第二军医大学东方肝胆医院胆道外科,上海,200433 |
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| 摘 要： | 目前认识到重症急性胰腺炎合并脑功能障碍存在脱髓鞘病理改变,检测脑脊液、血液髓鞘碱性蛋白以及头颅磁共振扫描有助于诊断脱髓鞘病变.重症急性胰腺炎脑功能障碍的诊断与治疗尚需大量临床经验的积累,以及发病机制的探索.
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| 关 键 词： | 胰腺炎 脑功能 脱髓鞘 |
Demyelination disease caused by cerebral functional disorder due to acute severe pancreatitis |
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| HAN Tian-quan,FENG Fei-ling,ZHANG Sheng-dao. Demyelination disease caused by cerebral functional disorder due to acute severe pancreatitis[J]. Chinese Journal of Hepatobiliary Surgery, 2010, 16(1). DOI: 10.3760/cma.j.issn.1007-8118.2010.01.027 |
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| Authors: | HAN Tian-quan FENG Fei-ling ZHANG Sheng-dao |
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| Abstract: | Severe acute pancreatitis is sometimes complicated by a syndrome of cerebral dysfunction, referred to as pancreatic encephalopathy. Demyelination is found in autopsy and considered as basic pathologic evidence in patients with pancreatic encephalopathy. Myelin basic protein detection in cerebrospinal fluid and blood, combined with magnetic resonance imaging scan might indicate the demyelinatic change. Further large-scale study on both pathogenesis and diagnosis of this disease is needed. |
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| Keywords: | Pancreatitis Cerebral functional Demyelination |
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