362株铜绿假单胞菌的感染分布及耐药性分析

目的:了解铜绿假单胞菌的分布,对铜绿假单胞菌的耐药性进行分析研究,为临床用药提供参考。方法:回顾性分析2006年铜绿假单胞菌在我院各病区及标本中的分布,用琼脂扩散法(K-B法)检测14种临床常用抗生素的耐药性。结果:我院2006年分离的362株铜绿假单胞菌中,痰液的阳性率最高,为77.3%(280/362),其次为创面分泌物、脓液,阳性率分别为13.3%(48/362)和3.6%(13/362),病室中神经内科检出率最高,为27.9%(101/362)。铜绿假单胞菌对14种常用抗生素的耐药率由5.5%到77.2%不等。结论:铜绿假单胞菌已经成为医院感染的重要病原菌,其不仅耐药率高,而且呈多重耐药,应加强医院感染的管理,定期开展耐药性监测,指导临床合理使用抗生素。

The Analysis of Drug Resistance and Distribution of 362 Strains Pseudomonas aeruginosa

Objective To investigate the distribution and the drug resistance of in hospital acquired infections of Pseudomonas aeruginosa.Methods To retrospective analysis drug resistance and distribution of the different wards and samples of Pseudomonas aeruginosa in Xiangya third hospital,2006.The Pseudomonas aeruginosa was identified by VITEK compact 2,K-B method detected the drug resistance of Pseudomonas aeruginosa to 14 antibiotics.Results A total 362 strains clinical isolates of Pseudomonas aeruginosa were collected from Jan 2006 to Jun 2006 in the Xiangya third hospital.The isolate rate of Pseudomonas aeruginosa from sputum,secretion,Abscess were 77.3%,13.3%,3.6%,respectively.The isolate rate of Neurology samples was 27.9%,which was highest.While the resistant rate of Pseudomonas aeruginosa to 14 antibiotics from 5.5% to 77.2%.Conclusion Hospital acquired infections of Pseudomonas aeruginosa is one of important pathogens that cause extensive resistance to many kinds of antibiotics.It's necessary to strengthen the clinic monitoring and select reasonable antibiotic for timely clinical treatment.