| 移植物抗肿瘤效应及其在实体瘤治疗中的意义 |
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| 引用本文： | 翟光林,姜藻.移植物抗肿瘤效应及其在实体瘤治疗中的意义[J].东南大学学报(医学版),2004,23(4):282-285. |
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| 作者姓名： | 翟光林 姜藻 |
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| 作者单位： | 东南大学临床医学院,江苏,南京,210009 |
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| 摘 要： | 异基因造血干细胞移植(Allo-HSCT)因具有独特的移植物抗恶性病效应常用来治疗某些恶性血液病，近年来Allo-HSCF在临床上尝试性地用来治疗某些实体瘤并取得了一定的疗效，现就Allo-HSCT所具有的移植物抗肿瘤效应及其免疫机制以及对实体瘤所产生的影响方面的文献报道作一综述。
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| 关 键 词： | 移植物 抗肿瘤效应 实体瘤 治疗 免疫机制 异基因造血干细胞移植 |
| 文章编号： | 1671-6264(2004)04-0282-04 |
| 修稿时间： | 2003年11月20 |
Graft-versus-tumor effect and its significance in the treatment of solid tumor |
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| ZHAI Guang-lin,JIANG Zao.Graft-versus-tumor effect and its significance in the treatment of solid tumor[J].Journal of Southeast Univ: Medical Sci Ed,2004,23(4):282-285. |
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| Authors: | ZHAI Guang-lin JIANG Zao |
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| Abstract: | Allogeneic hematopoietic stem cell transplantation(Allo-HSCT) has proved to have a unique immune-mediated antitumor effect in patients with hematologic malignancies. However,recently more investigators have come to recognize that antineoplastic effect mediated by immunopotent donor T-cells transplanted with the stem cell allograft can be induced against solid malignancies and achieved some therapeutic effect.This article reviews the graft-versus-tumor effect and its immunotherapeutic mechanism to investigate the potential of allogeneic immunotherapy for treating solid tumor. |
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| Keywords: | hematopoietic stem cell transplantation transplants neoplasms/therapy lymphocyte transfusion review literature |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
