| 慢性正己烷中毒患者脑诱发电位慢性正己烷中毒患者脑诱发电位的临床观察 |
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| 引用本文： | 李廷辉,肖小华. 慢性正己烷中毒患者脑诱发电位慢性正己烷中毒患者脑诱发电位的临床观察[J]. 职业与健康, 2010, 26(15): 1703-1704 |
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| 作者姓名： | 李廷辉 肖小华 |
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| 作者单位： | 1. 广东省深圳市职业病防治院,518001
2. 深圳市第二人民医院 |
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| 基金项目： | 深圳市科技局课题项目 |
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| 摘 要： | 目的观察慢性正己烷中毒患者的脑诱发电位的改变,探讨其改变的机理。方法对38例慢性正己烷中毒患者(正己烷中毒组)进行了体感诱发电位(somatosensory evoked potential,SEP)及脑干听觉诱发电位(brain auditory evoked potential,BAEP)检测,并与20例正常健康人(正常对照组)进行比较。结果正己烷中毒组SEP外周(N9、N13)及皮层(P20、P25)电位的潜伏期及波幅较正常对照组显著延长(P0.001);正己烷中毒组BAEP的Ⅰ、Ⅲ、Ⅴ波的潜伏期及波幅也均较正常对照组显著延长(P0.001)。结论慢性正己烷中毒患者的脑诱发电位的异常提示存在慢性脑损害,需采用相应的脑保护措施进行预防和治疗。
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| 关 键 词： | 正己烷中毒 脑诱发电位 |
Clinical Observation of Brain Evoked Potential in Patients with Chronic N-hexane Poisoning |
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| LI Ting-hui,XIAO Xiao-hua. Clinical Observation of Brain Evoked Potential in Patients with Chronic N-hexane Poisoning[J]. Occupation and Health, 2010, 26(15): 1703-1704 |
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| Authors: | LI Ting-hui XIAO Xiao-hua |
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| Affiliation: | (Shenzhen Hospital for Occupational Disease Prevention and Treatment,Guangdong,518001,China) |
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| Abstract: | [Objective]To observe the change of brain evoked potential in patients with chronic n-hexane poisoning,and investigate the mechanism of change.[Methods]Totally 38 patients with chronic n-hexane poisoning（N-hexane poisoning group） were tested for somatosensory evoked potential（SEP） and brain auditory evoked potential（BAEP）,the results were compared with healthy people（Normal control group）.[Results]Comparing with normal control group,latency and amplitude of SEP peripheral（N9,N13） and cortical（P20,P25） of N-hexane poisoning group were significantly increased（P〈0.001）,as well as latency and amplitude of BAEPⅠ,Ⅲ,Ⅴ waves.[Conclusion]Brain evoked potential abnormalities of patients with chronic n-hexane poisoning indicates chronic brain damage which needs relevant brain protection for prevention and treatment. |
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| Keywords: | N-hexane poisoning Brain evoked potential |
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