复方益肝灵胶囊预防抗结核药对肝损害疗效观察

目的：观察复方益肝灵胶囊预防抗结核药物对肝功能损害的疗效。方法：242例结核病患者在全程常规抗痨的同时。随机分为复方益肝灵胶囊治疗组和常规护肝对照组，6～12个月为1疗程。治疗结束后分别统计并进行比较它们的临床症状、体征和肝功能变化情况。结果：观察6～12个月，显示两组差异有显著性（P〈0．05）。结论：在全程常规抗痨的同时口服复方益肝灵胶囊，能有效的预防抗结核药物对肝功能的损害，无反弹现象，未见不良反应,具有较高的临床价值。

Observation of the curative effect of compound yiganling capsule in the prevention of hepatic lesion caused by antituberculotic

Objective:To observe the curative effect of compound yiganling capsule in the prevention of hepatic lesion caused by antituberculotic. Methods:242 patients with tuberculosis in full routine antituberculotic therapy were randomly divided into the treatment group and control group. The treatment group was treated with compound yiganling capsule and the control group with routine liver-protective therapy,the course of treatment was 6~12 months. After treatment their clinical symptoms,signs and changes of the liver function were counted and compared respectively. Results:There was a significant difference between two groups(P<0.05). Conclusion:Taking compound yiganling capsule in full routine antituberculotic therapy can effectively prevent the hepatic lesion caused by antituberculotic,without recurrence phenomenon and adverse reaction. It is of higher clinical value.