抗菌药物应用横断面调查

目的了解医院抗菌药物应用情况及合理性。方法采用横断面调查方法,对2006年12月19日0-24时医院门急诊和住院患者进行抗菌药物使用情况调查。结果急诊抗菌药物横断面使用率最高(54.67%),联合用药比例也较高(23.42%);涉及抗菌药物10大类,其中应用最多的是头孢菌素类(61.92%);妇产科抗菌药物使用率最高(37.96%),呼吸内科抗菌药物使用指数(DUI)最高(39.90%);全院病原学平均送检率为6.67%。结论医院急诊抗菌药物横断面使用率偏高,妇产科和呼吸内科抗菌药物使用过多,且起点偏高,有抗菌药物过度使用的可能性,病原学送检率低,需要进一步加强抗菌药物合理应用的管理。

Antibiotic Agents in a Hospital:A Cross Section Investigation of Their Clinical Application

OBJECTIVE To investigate the clinical application of antibiotic agents in a hospital.METHODS A cross section investigation method was used to survey the clinical application of antibiotic agents for emergency,out-patient clinic and hospitalization patients in a hospital within a day.RESULTS The usage rate of antibiotic agents for emergency patients was the maximum(54.67%) and the percentage of drug combination was multitude(23.42%).It was involved in 10 categories of antibiotic agents,cephalosporin was used at most(61.92%).The usage rate of antibiotic agents in Department of Gynecology and Obstetrics(OG) was the maximum(37.96%).Department with top defined DDD rate was Respiration Medical Department(RMD,39.90%).The average rate of etiological examination in the whole hospital was 6.67%.CONCLUSIONS It is higher in the usage rate of antibiotic agents for emergency patients.It is much more usage of antibiotic agents in OG and RMD,furthermore,the antibiotic agents are excessively used and the rate of etiological examination is low.Management should be further strengthened for rational use of antibiotic agents.