All-trans retinoic acid in acute promyelocytic leukemia: Preliminary results in Cuba |
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| Authors: | P. Hernández J. Carnot E. Dorticós E. Espinosa A. González I. Rodríguez |
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| Affiliation: | (1) Instituto de Hematologia e Inmunologia, Apartado 8070, C.P. 10800 Ciudad de La Habana, Cuba;(2) Hospital Clínico Quirúrgico, !["ldquo"]("/content/x34q4443066q473l/xlarge8220.gif") Hermanos Ameijeiras!["rdquo"]("/content/x34q4443066q473l/xlarge8221.gif") , Ciudad de La Habana, Cuba |
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| Abstract: | ![]()
Summary Seven patients with acute promyelocytic leukemia (APL) were treated with all-trans retinoic acid (ATRA). Five (71.4%) achieved complete remission (CR). Most side effects were transient and well tolerated. Hyperleukocytosis was the major adverse effect. These observations confirm the efficacy of ATRA for inducing CR in APL. |
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| Keywords: | Retinoic acid Acute promyelocytic leukemia Disseminated intravascular coagulation |
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