达格列净治疗老年糖尿病的效果分析及其对肾功能的影响

目的 探讨达格列净治疗老年糖尿病的临床效果及其对肾功能的影响.方法 从该院2019年6月—2020年1月门诊糖尿病患者中筛选年龄≥65岁患者68例,分为对照组(二甲双胍治疗)32例、治疗组(达格列净治疗)36例,比较两组的治疗效果、不良反应及对肾功能影响.结果 两组治疗后的临床效果对比,对照组治疗总有效率87.50％(...

Analysis of the Effect of Dapagliflozin in the Treatment of Senile Diabetes and Its Influence on Renal Function

Objective To investigate the clinical effect of dapagliflozin in the treatment of senile diabetes and its influence on renal function.Methods From June 2019 to January 2020,68 patients with diabetes aged≥65 years were selected from the outpatient diabetic patients in the hospital.They were divided into control group(metformin treatment)32 cases and treatment group(dapagliflozin treatment)36 cases.Comparison of the treatment effects,adverse reactions and effects on renal function of the two groups.Results Compared the clinical effects of the two groups after treatment,the total effective rate of the control group was 87.50%(28/32)lower than that of the treatment group 97.22%(35/36),the difference was statistically significant(P<0.05);the incidence of adverse reactions between the two groups in comparison,6.25%(2/32)of the control group was slightly higher than 5.56%(2/36)of the treatment group,and there was no statistically significant difference(P>0.05);the renal function indexes of the two groups after treatment were compared with those before treatment.The quantitative levels of creatinine and 24 h urine protein were lower than the levels before treatment,and the difference was statistically significant(P<0.05),but there was no statistically significant difference in the comparison of the above indicators of renal function between the two groups after treatment(P>005).Conclusion The treatment effect of dapagliflozin in elderly diabetes is significant,and the renal function of patients can be improved.The drug is safe and worthy of promotion.