胰岛素+达格列净治疗2型糖尿病的效果和对患者血糖的影响探讨

目的 探讨胰岛素+达格列净治疗2型糖尿病的效果和对患者血糖的影响.方法 将该院2018年10月—2020年6月期间治疗2型糖尿病患者88例作为研究对象,所有患者均采用常规降糖药物胰岛素进行治疗,根据是否联合应用达格列净药物分为两组,每组44例,对照组给予常规降糖药物进行治疗,试验组则在对照组基础上联合应用达格列净片,所...

Study on the Effect of Insulin+Dapagliflozin in the Treatment of Type 2 Diabetes and Its Influence on Patients'Blood Glucose

Objective To investigate the effect of insulin+dapagliflozin in the treatment of type 2 diabetes and its influence on patients'blood sugar.Methods 88 patients with type 2 diabetes were treated in the hospital from October 2018 to June 2020 as the research objects.All patients were treated with the conventional hypoglycemic drug insulin,and were divided into two groups according to whether they were combined with dapagliflozin,44 cases in each group,the control group was treated with conventional hypoglycemic drugs.The test group was combined with dapagliflozin tablets on the basis of the control group.All patients were treated for 4 consecutive weeks.The changes of blood lipid indexes(TC,TG,LDL-C)and fasting blood glucose of each group were observed before and after treatment,the blood glucose change 2 h after meal,and analyzed the patient's daily life quality and the occurrence of adverse reactions at the same time.Results The fasting blood glucose and postprandial blood glucose levels of the test group were significantly lower than those of the control group.The difference was statistically significant(P<0.05).There was no statistically significant difference in the blood lipid indexes of the test group before treatment(P>0.05).After treatment with different drugs,the blood lipid indexes of the patients in the test group were significantly improved compared with the control group,the difference was statistically significant(P<0.05).Conclusion The study of insulin+dapagliflozin has a good therapeutic effect.It not only effectively controls blood glucose in the normal fluctuation range,but also reduces blood lipids,regulates body metabolism,has high safety and feasibility,and improves the quality of patients'daily life.