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虫草属真菌的生物活性及机制研究现状与展望
引用本文:肖建辉,李彦,肖瑜,钟建江.虫草属真菌的生物活性及机制研究现状与展望[J].中国中药杂志,2013,38(5):640-647.
作者姓名:肖建辉  李彦  肖瑜  钟建江
作者单位:1. 遵义医学院附属医院贵州省细胞工程重点实验室,贵州遵义,563000
2. 上海交通大学微生物代谢国家重点实验室,上海,200240
基金项目:国家自然科学基金项目(81086260); 教育部新世纪优秀人才支持计划(NCET-010-100);贵州省社会发展"十一五"攻关项目(黔科合SZ字[2009] 3048);贵州省科技联合基金(黔科合J字LKZ[2011]36号)
摘    要:虫草是一类珍稀的药用真菌资源,其代谢产物和牛物活性具有多样性特点,在功能性食品和牛物医药领域展现出巨大的应用前景.虫草物种资源丰富,其中冬虫夏草是我国最名贵三大补益类中药之一.该文重点针对虫草及其代谢产物的牛物活性与作用机制的最新进展进行述评,并对该类资源研发过程存在的问题进行了分析,为今后发展提供了新思路.

关 键 词:虫草  代谢产物  生物活性  作用机制
收稿时间:2012/7/14 0:00:00

Advance and prospect of studies on bioactivity and mechanism of Cordyceps Fungi
XIAO Jian-hui,LI Yan,XIAO Yu and ZHONG Jian-jiang.Advance and prospect of studies on bioactivity and mechanism of Cordyceps Fungi[J].China Journal of Chinese Materia Medica,2013,38(5):640-647.
Authors:XIAO Jian-hui  LI Yan  XIAO Yu and ZHONG Jian-jiang
Institution:Key Laboratory of Cell Engineering of Guizhou Province, Affiliated Hospital of Zunyi Medical College, Zunyi 563000, China;Key Laboratory of Cell Engineering of Guizhou Province, Affiliated Hospital of Zunyi Medical College, Zunyi 563000, China;Key Laboratory of Cell Engineering of Guizhou Province, Affiliated Hospital of Zunyi Medical College, Zunyi 563000, China;State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai 200240, China
Abstract:Cordyceps is a precious medical fungi resource, with diverse metabolites and bioactive. There is huge prospect for its applicaiton in functional food and biomedicine fields. Cordyceps has abundant species resources, particularly Cordyceps sinensis is one of three most precious traditional Chinese restoratives in China. The essay summarizes the latest studies on bioactivity and mechanism of Cordyceps adn its metabolites, and analyzes problems during R&D of the resources, in order to bring forth new ideas to future development.
Keywords:Cordyceps  metabolite  bioactivity  mechanism
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