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Systemic amyloidosis presents a huge amyloidoma in the nasopharynx: A case report
引用本文:镡旭民 杨桦 邓安春 叶明福. Systemic amyloidosis presents a huge amyloidoma in the nasopharynx: A case report[J]. 中国人民解放军军医大学学报, 2004, 19(3): 194-196
作者姓名:镡旭民 杨桦 邓安春 叶明福
作者单位:[1]DepartmentofOtorhinolaryngology,XianqiaoHospital,ThirdMilitaryMedicalUniversity,Chongqing400038,China [2]DepartmentofClinicalPatholoy,XianqiaoHospital,ThirdMilitaryMedicalUniversity,Chongqing400038,China
摘    要:
A tumor-like presentation of systemic amyloidosis in the nasopharynx is exceedingly rare. A male of 52-yearold with a recurrent mass in the nasopharynx underwent surgical resection 2 years ago. Immunohistochemical examination revealed M protein band and kappa immunoglobulin light chain. The sections of the biopsy of the mass in the nasopharynx and anterior abdominal wall were stained with Congo red and examined with microscopy. Amyloid deposits were found. It was diagnosed as systemic amyloidoma. Colchicine, melphalan and prednisone were administered. The mass decreased its size in the 8 months of follow-up. This case suggests that a solitary tumor in the nasopharynx might be an early sign of systemic amyloidosis because of the slow progression of the disease. The existence of a solitary amyloidoma in any location of the body should lead the doctor to look for other symptoms and signs of systemic amyloidosis.

关 键 词:全身淀粉样变性 鼻咽部 进行性疾病 结石病

Systemic amyloidosis presents a huge amyloidoma in the nasopharynx:A case report
CHAN Xu-min ,YANG Hua ,DENG An-chun ,YE Ming-fu. Systemic amyloidosis presents a huge amyloidoma in the nasopharynx:A case report[J]. Journal of Medical Colleges of PLA(China), 2004, 19(3): 194-196
Authors:CHAN Xu-min   YANG Hua   DENG An-chun   YE Ming-fu
Affiliation:CHAN Xu-min 1,YANG Hua 1*,DENG An-chun 1,YE Ming-fu 2 1Department of Otorhinolaryngology,Xianqiao Hospital,Third Military Medical University,Chongqing 400038,China 2Department of Clinical Pathology,Xianqiao Hospital,Third Military Medical University,Chongqing 400038,China
Abstract:
A tumor-like presentation of systemic amyloidosis in the nasopharynx is exceedingly rare. A male of 52-year-old with a recurrent mass in the nasopharynx underwent surgical resection 2 years ago. Immunohistochemical examination revealed M protein band and kappa immunoglobulin light chain. The sections of the biopsy of the mass in the nasopharynx and anterior abdominal wall were stained with Congo red and examined with microscopy. Amyloid deposits were found. It was diagnosed as systemic amyloidoma. Colchicine, melphalan and prednisone were administered. The mass decreased its size in the 8 months of follow-up. This case suggests that a solitary tumor in the nasopharynx might be an early sign of systemic amyloidosis because of the slow progression of the disease. The existence of a solitary amyloidoma in any location of the body should lead the doctor to look for other symptoms and signs of systemic amyloidosis.
Keywords:amyloidosis  solitary amyloidoma  nasopharynx
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