亚甲基蓝法在乳腺癌前哨淋巴结活检术60例的临床应用

目的探讨乳晕下注射亚甲基蓝示踪法进行前哨淋巴结活检术(SLNB)在乳腺癌治疗中的临床意义。方法以60例可手术乳腺癌患者作为研究对象,临床体检腋窝淋巴结(ALN)阴性,均单独采用亚甲基蓝作为前哨淋巴结(SLN)示踪剂。结果全部行乳腺癌改良根治术,行SLN和ALN活检,灵敏度为95.65%,准确率为91.07%,假阴性率为13.04%,假阳性率8.70%。SLNB与ALN转移检测比较效果相一致,准确率高。结论前哨淋巴结活检术准确率较高,能较准确地预测和判定乳腺癌腋窝淋巴结的转移情况。

An analysis on sentinel lymph node biopsy marked with methylene - blue in 60 cases of breast cancer

Objective To evaluate the efficacy of sentinel lymph node biopsy(SLNB) by using subareolar injection ofmethylene blue in the management of breast cancer.Methods Sixty cases of breast tumor without axillary lymph node(ALN) by palpation were enrolled in this study.Results All patients were treated by segment resection plus axillary lymph node dissection.Biopsies of sentinel lymph nodes and axillary lymph nodes were taken in all patients.The sensitivity of SLNB was 95.65%,its accurate rate was 91.07%,its false negative rate was 13.04%,and its false positive rate was 8.70%.There was no significant difference between the effect of detection of metastasis by sentinel lymph node or axillary lymph node biopsy.Conclusion Due to the high accuracy of sentinel lymph node biopsy in our team,the axillary lymph node metastasis of breast cancer can be predicted and judged.