| 胃癌组织中C-met的表达及临床意义 |
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| 引用本文： | 鲍敏,吴继锋. 胃癌组织中C-met的表达及临床意义[J]. 安徽医学, 2012, 33(6): 687-689 |
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| 作者姓名： | 鲍敏 吴继锋 |
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| 作者单位： | 安徽医科大学基础医学院,安徽医学高等专科学校,合肥,230022;安徽医科大学基础医学院,安徽医学高等专科学校,合肥,230022 |
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| 摘 要： | 目的研究C-met与胃癌临床病理生物学行为的关系,探讨C-met在胃癌发生发展中的临床意义。方法对78例经病理证实的胃癌组织采用免疫组织化学间接法检测C-met蛋白的表达。结果 C-met蛋白阳性率与患者性别、年龄、病变部位无明显关系(P0.05);与肿瘤的大小、分化程度、浸润深度、有无淋巴结转移有关(P0.05)。结论 C-met促进了胃癌组织的生长与转移,C-met蛋白可能成为评估胃癌发生发展的一项新的指标。
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| 关 键 词： | 胃癌 原癌基因 C-met |
Expression of C-met in gastric carcinoma and its clinical significance |
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| Bao Min , Wu Jifeng. Expression of C-met in gastric carcinoma and its clinical significance[J]. Anhui Medical Journal, 2012, 33(6): 687-689 |
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| Authors: | Bao Min Wu Jifeng |
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| Affiliation: | Anhui Medical University Basic Medical Sciences,Anhui Medical College,Hefei,230022,China |
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| Abstract: | Objective To study the relationship between C-met and the clinical,pathological,and biological behavior of gastric cancer and to explore the clinical significance of C-met in the development and progression of gastric cancer.Methods Immunohistochemitry by SP method was carried out on 78 pathologically confirmed gastric cancer cases to examine the expression of C-met.Results Expression of C-met was closely correlated with tumor size,differentiation,invasion and lymph node metastasis(P <0.05),while had no relation with sex,age and tumor site(P >0.05).Conclusion C-met promotes the growth and metastasis of gastric cancer and might be a new parameter in evaluating the prognosis of gastric cancer. |
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| Keywords: | Gastric carcinoma Proto-oncogene C-met |
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