酒精依赖患者注意网络研究

目的探索酒精依赖患者注意缺陷的特征以及可能机制。方法对确诊的21例酒精依赖患者进行简易精神状态量表(MMSE)测试和注意网络测试,并与21名正常对照组相比较。结果酒精依赖患者组定向网络时间[(30.4±36.9)ms]较对照组[(56.8±22.0)ms]明显缩短;执行控制网络时间[(160.6±78.8)ms]较对照组[(103.9±47.6)ms]明显延长,差异有统计学意义(P0.05)。而警觉网络效率与对照组的差异无统计学意义。结论酒精依赖患者定向网络和执行网络受损,提示酒精可能对额叶、顶叶等脑区有更为显著的影响。

Attention networks in patients with alcohol dependence

Objective To investigate the characteristics of attention networks impairment in the patients with alcohol dependence and the impossible mechanism that the brain was harmed by the alcohol. Methods Mini-mental state examination and the attention network test were used in 21 patients with alcohol dependence and 21 normal controls. Results The orienting network function was significantly lower(P<0.05) in the patients with alcohol dependence(30.4 ±36.9)ms than in normal controls(56.8 ±22.0)ms.The esecutive networks effects was higher(P<0.05) in the patients with alcohol dependence(160.6 ±78.8)ms than in controls(56.8 ±22.0)ms.The alerting networks effects was lower in alcohol-dependent patients and in normal controls,however without significant difference(P>0.05). Conclusion The orienting and executive network impairment was found in 21 patients with alcohol dependence,which suggests the frontal lobe and parietal lobe may be more significantly affected by the alcohol.