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慢性阻塞性肺疾病急性加重期患者病原体检测分析
引用本文:石宝平,钱叶长,王丽华,张有志,周丽,程克文,陈小东. 慢性阻塞性肺疾病急性加重期患者病原体检测分析[J]. 山东医药, 2010, 50(15): 18-20
作者姓名:石宝平  钱叶长  王丽华  张有志  周丽  程克文  陈小东
作者单位:1. 复旦大学附属华山医院宝山分院,上海,200431
2. 上海市宝山区中心医院
3. 上海市第一人民医院宝山分院
基金项目:上海市宝山区科委资助项目 
摘    要:目的了解慢性阻塞性肺疾病病情急性加重期患者(AECOPD)的病原学特点,为进一步提高其诊治水平提供思路。方法对165例AECOPD患者行痰细菌定量培养,血清支原体、衣原体、嗜肺军团菌抗体检测以及鼻咽拭子病毒RT—PCR检测,分析其特点。结果病原体检测阳性率为70.3%(116/165)。其中痰检细菌阳性率为47.3%;非典型病原体阳性率为21.2%;病毒检测阳性率为24.8%;细菌和非典型病原体均为阳性21例,阳性率为12.7%;细菌和病毒均为阳性17例,阳性率为10.3%。结论AECOPD患者病原体以细菌最为常见,以革兰阴性杆菌为主,非典型病原体多与细菌混和感染,病毒感染多见于呼吸困难的患者。非感染因素导致的AECOPD病情加重不容忽视。

关 键 词:慢性阻塞性肺病  病原体

Dection and analysis of pathogens in patients with acute exacerbation of chronic obstructive pulmonary disease
SHI Bao-ping,QIAN Ye-chang,WANG Li-hua,ZHANG You-zhi,ZHOU Li,CHENG Ke-wen,CHEN Xiao-dong. Dection and analysis of pathogens in patients with acute exacerbation of chronic obstructive pulmonary disease[J]. Shandong Medical Journal, 2010, 50(15): 18-20
Authors:SHI Bao-ping  QIAN Ye-chang  WANG Li-hua  ZHANG You-zhi  ZHOU Li  CHENG Ke-wen  CHEN Xiao-dong
Affiliation:SHI Bao-ping1,QIAN Ye-chang,WANG Li-hua,ZHANG You-zhi,ZHOU Li,CHENG Ke-wen,CHEN Xiao-dong(1 Huashan Hospital Baoshan Branch,Fudan University,Shanghai 200431,P.R.China)
Abstract:Objective To investigate the pathogenic characteristics in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD),so as to provide thinking for the development for its consultation.Methods One hundred and sixty-five patients with AECOPD were performed with quantitative sputum bacteria culture,mycoplama pneumoniae,chlamydia pneumoniae and legionella pneumophila specific antibodies test and RT-PCR virus detection.Characteristics of pathogens distribution were studied.Results The pos...
Keywords:chronic obstructive pulmonary disease  pathogen  
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