替米沙坦联用胺碘酮在心房颤动复律后维持窦性心律的疗效观察

目的：观察替米沙坦联用胺碘酮在心房颤动（AF）复律后维持窦性心律的作用及对左房内径的影响。方法：87例心房颤动（房颤）患者,复律后随机分为两组,对照组给予胺碘酮治疗,试验组给予胺碘酮＋替米沙坦治疗。观察两组治疗后房颤复发情况和左心房内径变化。结果：随访1年后试验组窦性心律的维持率为82.9%（34/41）明显高于对照组的72.5%（29/40）,差异有统计学意义（P〈0.05）;试验组治疗后较治疗前左房内径显著缩小（P〈0.05）,对照组治疗前后差异无统计学意义（P〉0.05）。结论：替米沙坦联用胺碘酮在房颤复律后维持窦性心律较单用胺碘酮更有效,并可逆转左房扩大。

Efficacy of Telmisartan with Amiodarone in the maintenance of sinus rhythm after cardioversion of atrial fibrillation

0bjective： To observe efficacy of Telmisartan with Amiodarone in the maintenance of sinus rhythm after cardioversion of atrial fibrillation（AF） and its influence on left atrial diameter.Methods： 87 patients with atrial fibrillation were randomly divided into two groups after cardioversion,control group was given Amiodarone;test group was given Amiodarone and Telmisartan treatment.To observe atrial fibrillation recurrence rate and changes of left atrial diameter.Results： After 1 year follow-up,maintenance rate of sinus rhythm in test group（82.9%） was significantly higher than the control group（72.5%）,there was statistically differences（P0.05）;Left atrial diameter of test group significantly reduced after treatment（P0.05）,but that control group had no difference before and after treatment（P0.05）.Conclusion： Efficacy of Telmisartan with Amiodarone in the maintenance of sinus rhythm after cardioversion of atrial fibrillation is better than Amiodarone,and it can change left atrial enlargement.