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参芪扶正注射液联合化疗治疗晚期食管癌的临床观察
引用本文:张盛奇,林丽芳,丘希辉,郑泓斌,方玫玫. 参芪扶正注射液联合化疗治疗晚期食管癌的临床观察[J]. 中国医药导报, 2011, 8(19): 74-76
作者姓名:张盛奇  林丽芳  丘希辉  郑泓斌  方玫玫
作者单位:汕头大学医学院肿瘤医院中西医结合科,广东汕头,515031
摘    要:目的:比较参芪扶正注射液联合化疗与单纯化疗治疗晚期食管癌的疗效及不良反应。方法:将83例晚期食管癌患者随机分为两组,治疗组42例,用参芪扶正注射液250 ml/d静脉滴注14 d,配合DDP+CF/5-Fu方案化疗,对照组41例,单纯用DDP+CF/5-Fu方案化疗。DDP+CF/5-Fu化疗方案为顺铂(DDP)25 mg/m2,d1~3,醛氢叶酸(CF)200 mg/m2,d1,5-氟尿嘧啶(5-Fu)500 mg d1,2750 mg/m2持续静滴d1~2,每3周重复1次,共2个化疗周期,治疗后评价疗效、中医症候、毒副反应及生活质量改善情况。结果:两组近期疗效无明显差异,但治疗组毒副反应减轻,生活质量提高,差异有统计学意义(P〈0.05),中医症候改善明显,差异有高度统计学意义(P〈0.01)。结论:参芪扶正注射液可减轻晚期食管癌患者DDP+CF/5-Fu方案化疗所致毒副作用,改善生活质量。

关 键 词:参芪扶正注射液  晚期食管癌  化疗

Clinical observation of advanced esophageal cancer treated with Shenqi Fuzheng Injection combined with chemotherapy
ZHANG Shengqi,LIN Lifang,QIU Xihui,ZHENG Hongbin,FANG Meimei. Clinical observation of advanced esophageal cancer treated with Shenqi Fuzheng Injection combined with chemotherapy[J]. China Medical Herald, 2011, 8(19): 74-76
Authors:ZHANG Shengqi  LIN Lifang  QIU Xihui  ZHENG Hongbin  FANG Meimei
Affiliation:ZHANG Shengqi,LIN Lifang,QIU Xihui,ZHENG Hongbin,FANG Meimei Department of Traditional Chinese and Western Medicine,the Tumor Hospital of Shantou University Medical College,Guangdong Province,Shantou 515031,China
Abstract:Objective:To compare the curative effect and side effect of combined treatment of Shenqi Fuzheng Injection and chemotherapy with only chemotherapy for patients with advanced esophageal cancer.Methods:83 cases of patients with advanced esophageal cancer were randomly divided into two groups.42 cases in treatment group were treated with Shenqi Fuzheng Injection 250 ml/d for 14 days and DDP+CF/5-Fu chemotherapy,41 cases in the control group were treated with DDP+CF/5-Fu chemotherapy alone.DDP+CF/5-Fu chemother...
Keywords:Shenqi Fuzheng Injection  Late esophageal cancer  Chemotherapy  
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