阿尔兹海默病与血管性痴呆的诊疗对比

目的：探讨阿尔兹海默病与血管性痴呆的诊断方法和治疗效果。方法：选取我院2006～2010年收治的阿尔兹海默病和血管性痴呆患者,观察比较其诊断指标和治疗效果。结果：AD和VaD患者MMSE-R评分无显著差异;AD组和VaD组脑电图异常率有统计学意义（P〈0.01）,AD组脑电图异常率低于VaD组;AD与VaD组患者血浆Hcy、VitB12和ChE差异有统计学意义（P〈0.05）;AD组与VaD组认知功能、记忆功能和社会行为能力改善比较差异有统计学意义（P〈0.05）,VaD组改善均好于AD组。结论：通过临床症状和生化检查在一定程度上能够鉴别AD和VaD患者,同时针对二者不同的病因和发病机制,采取相应的治疗措施有一定的效果,值得临床借鉴。

Comparative studies on diagnosis and curative effect for Alzheimer's disease and vascular dementia

Objective：To explore the diagnosis and curative effect of AD and VaD.Methods：Retrospective analysis of the patient＇s dates from 2006 to 2010 in our hospital,to observe diagnostic indexes and curative effect.Results：MMSE-R for AD and VaD was not different significantly.EEG for AD and VaD were statistical different significantly（P0.01）;Hcy,VitB12 and ChE for AD and VaD were statistical different significantly;Cognitive function、memory function、ability and social behaviors were statistical different significantly（P0.05）,curative effect of VaD was better than AD.Conclusion：Symptom and biochemistry can be used for differential diagnosis.Taking effective treatment according to pathogenesis should be good for AD and VaD and be used for reference.