老年NSTE-ACS患者GRACE危险分层与颈动脉内膜中层厚度的关系

目的探讨老年非ST段抬高急性冠状动脉综合征(NSTE-ACS)患者全球急性冠状动脉事件注册(GRACE)评分以及危险分层与颈动脉内膜中层厚度(IMT)的关系。方法入选83例在我院住院的老年NSTE-ACS患者,其中不稳定性心绞痛(UA)49例,非ST段抬高心肌梗死(NSTEMI)34例。入院后采用GRACE评分标准对患者进行风险评估,计算GRACE积分并进行危险分层。采用超声测定IMT,分析患者GRACE分层与IMT的关系。结果根据GRACE积分将所有老年NSTE-ACS患者分为高危、中危、低危三组,高危组IMT显著高于中危组[(1.15±0.29)mm与(0.94±0.14)mm,P<0.01],中危组显著高于低危组[(0.94±0.14)mm与(0.82±0.13)mm,P<0.05]。结论 IMT对老年NSTE-ACS患者的危险分层有一定预测价值。

Relationship between GRACE risk stratification and carotid intima-media thickness in elderly patients with non-ST-seg-ment elevation acute coronary syndrome

Objective To study the relationship between GRACE(global registry of acute coronary events) risk stratification and carotid intima-media thickness(IMT) in elderly patients with non-ST-segment elevation acute coronary syndrome(NSTE-ACS).Methods A total of 83 elderly NSTE-ACS patients admitted to our hospital,including 49 patients with UA(unstable angina) and 34 ones with non-ST-segment elevation myocardial infarction(NSTEMI),were enrolled in the study.GRACE risk score was used for risk assessment.The IMT of carotid arteries was determined with B-mode ultrasound.The relationship between GRACE risk stratification and IMT was analyzed.Results The patients were divided into three groups,i.e.high-risk group,mid-risk group and low-risk group according to the GRACE risk stratification.The IMT of the high-risk group was higher than that of the mid-risk group [(1.15 ±0.29) mm vs(0.94 ±0.14) mm,P < 0.01]and the IMT of the mid-risk group was higher than that of the low-risk group [(0.94 ± 0.14) mm vs(0.82 ± 0.13) mm,P < 0.05].Conclusion Measurement of IMT is of predictive value for risk stratification in elderly patients with NSTE-ACS.