|
|||||
|
|
| KIT在子宫肉瘤的表达及临床意义 | |
| 引用本文： | 宋英君,李军,王霞. KIT在子宫肉瘤的表达及临床意义[J]. 中国当代医药, 2011, 18(17): 33-35 |
| 作者姓名： | 宋英君 李军 王霞 |
| 作者单位： | 1. 青岛市市立医院,山东,青岛,266002 2. 山东省莱州市爱卫办,山东,莱州,261400 |
| 摘 要： | 目的：研究用甲磺酸伊马替尼治疗子宫肉瘤的可能性。方法：使用免疫组化的方法分析30例甲醛固定石蜡包埋的子宫肉瘤KIT的表达。结果：使用半定量免疫组化计分发现在所有检验的子宫肉瘤中只有1例KIT表达,而且较微弱,而被检验的子宫肉瘤中没有表现出很强的表达。结论：目前的资料表明甲磺酸伊马替尼不可能作为单一有效的药物对子宫肉瘤使用。 |
| 关 键 词： | 子宫肉瘤 KIT 甲磺酸伊马替尼 表达 |
KIT expression in uterine sarcoma and its clinical significance |
|
| SONG Yingjun,LI Jun,WANG Xia. KIT expression in uterine sarcoma and its clinical significance[J]. http://www.botanicus.org/, 2011, 18(17): 33-35 | |
| Authors: | SONG Yingjun LI Jun WANG Xia |
| Affiliation: | 1.Municipal Hospital of Qingdao,Shandong Province,Qingdao 266002,China;2.Laizhou City Patriotic Sanitation,Shandong Province,Laizhou 261400,China |
| Abstract: | Objective：To investigate the possibility of treating uterine sarcomas with imatinib mesylate.Methods：Expression of KIT was analyzed immunohistochemically（n=30） in formalin-fixed paraffin-embedded uterine sarcomas.Results：Used a semi-quantitative immunohistochemical score we found only 1 case of uterine sarcomas express used KIT,and relatively weak.While none of the uterine sarcoma tested showed strong expression.Conclusion：The current data suggest that it is unlikely that imatinib mesylate could be used effectively as a single agent in patients with uterine sarcoma. |
| Keywords: | KIT |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |