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针灸对血管性痴呆大鼠行为学及组织内乙酰胆碱酯酶含量的影响
引用本文:杨春壮,李明秋,王莹,夏珊珊,刘静男. 针灸对血管性痴呆大鼠行为学及组织内乙酰胆碱酯酶含量的影响[J]. 针灸临床杂志, 2011, 27(7): 71-73
作者姓名:杨春壮  李明秋  王莹  夏珊珊  刘静男
作者单位:牡丹江医学院,黑龙江牡丹江,157011
基金项目:黑龙江省中医药科研项目,编号:ZH10-W97; 黑龙江省卫生厅医学科研课题,编号:2006-401
摘    要:
目的:观察针刺百会、大椎、人中穴对血管性痴呆(VD)大鼠学习记忆能力及血和海马内乙酰胆碱酯酶(AchE)含量的影响,探讨其治疗血管性痴呆的机制。方法:用双侧颈总动脉缺血再灌注制作VD大鼠模型,将造模后的VD大鼠随机分为模型组、针灸组和西药组加以治疗。通过大鼠跳台检测行为学指标;酶免法检测血清和大脑海马组织AchE含量。结果:针灸组大鼠跳台检测反应期比模型组减少(P<0.05);针灸组血清和海马AchE含量比模型组降低(P<0.05)。结论:针刺百会、大椎、人中穴对血管性痴呆大鼠血和海马内AchE含量的改善是其治疗机制之一。

关 键 词:血管性痴呆  针灸  百会  大椎  人中  乙酰胆碱酯酶

The Effect of Acupuncture on Behavior and Contents of AchE of Rats with Vascular Dementia
YANG Chun-zhuang,LIMing-qiu,WANG Ying,XA Shan-shan,LIU Jing-nan. The Effect of Acupuncture on Behavior and Contents of AchE of Rats with Vascular Dementia[J]. Journal of Clinical Acupuncture and Moxibustion, 2011, 27(7): 71-73
Authors:YANG Chun-zhuang  LIMing-qiu  WANG Ying  XA Shan-shan  LIU Jing-nan
Affiliation:YANG Chun-zhuang,LI Ming-qiu,WANG Ying,XIA Shan-shan,LIU Jing-nan(Mudanjiang Medical University,Mudanjiang 157011,China)
Abstract:
Objective:To observe the effect of acupuncture at Baihui,Dazhui and Renzhong on metabolism of study memorizing ability and AchE in serum and hippocampus of VD rats. Methods:The model was made by common carotid artery ischemia in pairs.The rats were randomized into model group,acupuncture group and western medicine group,the rats study and memorizing ability of step down and enzyme-immunossay methods in serum,the content of hippocampus AchE were examined. Results:The acupuncture reaction period of stepping d...
Keywords:Vascular dementia  Acupuncture  Baihui  Dazhui  Renzhong  AchE  
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