恶性肿瘤患者血清肿瘤特异性生长因子的检测及临床意义

目的　评价一种新的肿瘤标记物——血清肿瘤特异性生长因子 ( TSGF)在恶性肿瘤诊断中的临床意义。方法　以正常人急、慢性炎症和良性肿瘤患者作对照 ,测定了多种恶性肿瘤患者血清 TSGF的含量。结果　各种恶性肿瘤患者之间血清 TSGF的水平差异无显著性 ( P>0 .0 5) ,但均明显高于正常对照组、慢性炎症组及良性肿瘤组 ( P<0 .0 1) ,而与急性炎症组差异无显著性 ( P>0 .0 5)。结论　排除急性炎症后 ,TSGF是鉴别良性和恶性肿瘤的可靠指标 ,对恶性肿瘤的诊断有一定的临床价值。

Detection and clinical significance of serum tumor-specific growth factor in patients with malignant tumor

Objective To evaluate the clinical significance of a new tumor marker——serum tumor specific growth factor (TSGF) in diagnosis of malignant tumors.Methods The TSGF level was detected in patients with malignant tumor,while patients with benign tumor,acute or chronic inflammation and healthy persons were selected as control groups.Results The TSGF level showed no remarkable difference among malignant tumor groups (P>0 05);but the malignant tumor groups′ TSGF level was obviously higher than that of the benign tumor group,chronic inflammation group and control group (P<0 01),being of no remarkable difference from acute inflammation group (P>0 05).Conclusion Aside from the possible confusion of acute inflammation,TSGF ,as a reliable marker,will be helpful to distinguish malignant tumor from benign one,having certain clinical value in diagnosis of malignant tumors.