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Effects of Combined Radiation-Burn Injury on Intestinal Epithelium in Mice
引用本文:粟永萍,程天民. Effects of Combined Radiation-Burn Injury on Intestinal Epithelium in Mice[J]. 中国人民解放军军医大学学报, 1987, 0(1)
作者姓名:粟永萍  程天民
作者单位:Department of Radiation Medicine Third Military Medical College,Chongqing,Department of Radiation Medicine,Third Military Medical College,Chongqing
摘    要:Seven hundred and forty-six mice,weighing 30-35g,were randomlydivided into 4 groups.The animals of the first three groups were inflicted withradiation injury(12 Gy total body irradiation from a ~(60)Co source),burn injury(15% TBSA third degree burns),and combined injury of the 2 agents ,mentionedabove respectively.The 4th group served as normal control.The mortality and the dynamic changes of the intestinal epithelium of theexperimental animals were studied.It was found that the clinical course of thecombined injury group was quite different from that of the other two.Themortality of the combined injury group was higher and the damage on theintestinal epithelium more severe than those of the radiation injury group in thefirst 48 h after infury.In the second 48 h,the mortality of the combined injurygroup became lower and recovery of the injured intestinal epithelium faster.


Effects of Combined Radiation-Burn Injury on Intestinal Epithelium in Mice
Su Yongping Cheng Tianmin. Effects of Combined Radiation-Burn Injury on Intestinal Epithelium in Mice[J]. Journal of Medical Colleges of PLA(China), 1987, 0(1)
Authors:Su Yongping Cheng Tianmin
Affiliation:Su Yongping Cheng Tianmin Department of Radiation Medicine,Third Military Medical College,Chongqing
Abstract:Seven hundred and forty-six mice,weighing 30-35g,were randomly divided into 4 groups.The animals of the first three groups were inflicted with radiation injury(12 Gy total body irradiation from a ~(60)Co source),burn injury (15% TBSA third degree burns),and combined injury of the 2 agents ,mentioned above respectively.The 4th group served as normal control. The mortality and the dynamic changes of the intestinal epithelium of the experimental animals were studied.It was found that the clinical course of the combined injury group was quite different from that of the other two.The mortality of the combined injury group was higher and the damage on the intestinal epithelium more severe than those of the radiation injury group in the first 48 h after infury.In the second 48 h,the mortality of the combined injury group became lower and recovery of the injured intestinal epithelium faster.
Keywords:combined effect  radiation injury  combined radiation-burn injury  radiation sickness of intestinal type  injury of intestinal epithelial cells  burns
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