Central Nervous System and Ocular Manifestations in Puumala Hantavirus Infection |
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| Authors: | Nina Hautala Terhi Partanen Anna-Maria Kubin Heikki Kauma Timo Hautala |
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| Affiliation: | 1.Medical Research Center, PEDEGO Research Unit, Department of Ophthalmology, Oulu University Hospital and University of Oulu, 90029 Oulu, Finland; (N.H.); (A.-M.K.);2.Research Unit of Internal Medicine, Department of Internal Medicine, Division of Infectious Diseases, Oulu University and Oulu University Hospital, 90014 Oulu, Finland; (T.P.); (H.K.);3.Research Unit of Biomedicine, University of Oulu, 90029 Oulu, Finland |
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| Abstract: | ![]()
Puumala hantavirus (PUUV), carried and spread by the bank vole (Myodes glareolus), causes a mild form of hemorrhagic fever with renal syndrome (HFRS) called nephropathia epidemica (NE). Acute high fever, acute kidney injury (AKI), thrombocytopenia, and hematuria are typical features of this syndrome. In addition, headache, blurred vision, insomnia, vertigo, and nausea are commonly associated with the disease. This review explores the mechanisms and presentations of ocular and central nervous system involvement in acute NE. |
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| Keywords: | hantavirus central nervous system encephalitis visual disorders intraocular pressure myopic shift |
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