The influence of the functional condition of the central nervous system on the development of toxic edema of the lungs and pleurisy

Summary The author studied the effect of the functional condition of the central nervous system and especially of the changes in the correlation of the main nervous processes — excitation and inhibition — on the development of toxic edema of the lungs and pleurisy. The changes in the functional state of the central nervous system were produced by the administration of sodium bromide, caffeine, and Phenamine (Benzedrine); stimulation of the vagosympathetic trunk was also used. Acute edema of the lungs and pleurisy were induced by sodium bromide administration. The results of experiments have demonstrated that alteration of the functional condition of the nervous system, particularly of the correlation of the excitation-inhibition processes, had a definite influence on the development of toxic edema of the lungs and pleurisy.(Presented by Academician V. N. Chernigovskii) Translated from Byulleten Eksperimental'noi Biologii i Meditsiny, Vol. 51, No. 2, pp. 27–32, February, 1961