| 补肾调肝敛乳方对泌乳素分泌影响的动物实验研究 |
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| 引用本文： | 陈新,刘菊芳,桂耀庭,张永锋. 补肾调肝敛乳方对泌乳素分泌影响的动物实验研究[J]. 中国实验方剂学杂志, 1998, 4(3): 30-32 |
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| 作者姓名： | 陈新 刘菊芳 桂耀庭 张永锋 |
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| 作者单位： | 深圳市红十字会医院，市中西医结合临床研究所 深圳 518029 |
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| 摘 要： | 利用体外垂体组织培养技术及灭吐灵诱导ＨＰＲＬ小鼠模型，以溴隐亭为对照，观察敛方的作用。结果：剑乳方不仅可以抑制离体垂体ＰＲＬ的分泌，还可拮抗灭吐灵导致的小鼠血清ＰＲＬ升高、子宫减重、受孕率下性周期紊乱，上述作用与溴隐亭相似，敛乳方还可促使示成熟雌鼠阴道上皮细胞角化。
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| 关 键 词： | 补肾调肝敛乳方 垂体 泌乳素 药理 中药 |
Effects of Bushen Tiaogan Lianru Decoction (BTLD) on the Secretion of Prolactine in Experimental Animals |
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| Chen Xin,Liu Jufang,Gui Yaoting,Zhang Yongfeng. Effects of Bushen Tiaogan Lianru Decoction (BTLD) on the Secretion of Prolactine in Experimental Animals[J]. China Journal of Experimental Traditional Medical Formulae, 1998, 4(3): 30-32 |
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| Authors: | Chen Xin Liu Jufang Gui Yaoting Zhang Yongfeng |
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| Affiliation: | Shenzhen Red Cross Hospital,Shenzhen Institute of Integrated Chinese and Western Medicine,Shenzhen,518029 |
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| Abstract: | An in vitro system of pituitary tissue culture and a HPRL(hyperprolactinemia) mice model induced by metoclopramide were used to observe the effects of BTLD.BTLD not only inhibited the PRL(prolactin) secretion by cultured pituitary tissue,but also can antagonize increase of serum PRL,decrease of womb weight and rate of pregnancy,and disorder of sex circle caused by administration of metoclopramide,these actions of BTLD were similar to those of bromocriptine,besides,BTLD could also spur cornification of vaginal epithelium in immature mice. |
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| Keywords: | BTLD(Bushen Tiaogan Lianru decoction) pituitary prolactin |
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