3.OT场强磁共振应用MRA血管成像与3D-ASL脑灌注成像技术在诊断缺血性脑血管疾病中的应用

目的 3.OT磁共振血管成像(MRA)与三维动脉自旋标记技术(3D-ASL)脑灌注成像技术在诊断缺血性脑血管疾病中的应用。方法选取我院2014年7月至2015年7月60例缺血性脑血管疾病患者为研究对象,分别采用3.OT场强磁共振应用MRA血管成像与CD-ASL脑灌注成像技术诊断,观察MRA与3D-ASL诊断结果,及对短暂性脑缺血发作、大面脑梗死、小面积脑梗死诊断的一致性,并对其图像进行分析。结果 3D-ASL诊断灵敏度为93.33%、特异度为90.00%,均高于MRA的70.00%、66.67%,有统计学意义(P0.05)。在15例短暂性脑缺血发作患者中,11例诊断一致,4例诊断不一致;4诊断不一致的患者经3D-ASL诊断为灌注减低,但经MRA诊断显示为无异常。21例大面脑梗死患者,经MRA与3D-ASL均一致。在24例小面积脑梗死患者中,17例诊断不一致,7例诊断一致。结论 3DASL诊断灵敏度、特异度均高于MRA,3DASL与MRA对大面积脑梗死的诊断一致性较高,具有较好的临床应用价值。

Application of 3.0T MRA and 3D-ASL Cerebral Perfusion Imaging in the Diagnosis of Ischemic Cerebrovascular Disease

Objective To explore the application of 3.0T magnetic resonance angiography (MRA) and three-dimensional arterial spin labeling (3D-ASL) cerebral perfusion imaging in the diagnosis of ischemic cerebrovascular disease. Methods Sixty patients with ischemic cerebrovascular disease admitted in our hospital between July 2014 and July 2015 were selected as the study subjects. 3.0T MRA and CD-ASL cerebral perfusion imaging were respectively used for diagnosis, and the results were observed. The consistency in the diagnosis of transient ischemic attack, large-area cerebral infarction, small-area cerebral infarction and images were analyzed. Results The diagnostic sensitivity and specificity of 3D-ASL (93.33%, 90.00%) were higher than those of MRA (70.00%, 66.67%) (P<0.05). In 15 cases with transient ischemic attack, the diagnosis of 11 cases were consistent while of 4 cases were not consistent, and the 4 cases, were diagnosed as perfusion decline by 3D-ASL. However, the diagnosis of MRA showed no abnormality. The diagnosis of MRA and 3D-ASL in 21 cases with large-area cerebral infarction were consistent. In 24 cases with small-area cerebral infarction, the diagnosis of 17 patients was not consistent while of 7 cases was consistent. Conclusion The diagnostic sensitivity and specificity of 3D-ASL are higher than those of MRA. The consistency of 3D-ASL and MRA in the diagnosis of large-area cerebral infarction is high.