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卵巢子宫内膜异位囊肿CA125的测定及其临床价值研究
引用本文:张俊娇,周潘梅. 卵巢子宫内膜异位囊肿CA125的测定及其临床价值研究[J]. 中国基层医药, 2013, 20(20): 3109-3111
作者姓名:张俊娇  周潘梅
作者单位:321200,浙江省武义县第一人民医院妇产科
摘    要:目的 探讨检测糖类抗原(CA125)在卵巢子宫内膜异位囊肿诊治中的应用价值,为临床诊疗提供一定的参考.方法 卵巢子宫内膜异位囊肿51例为观察组,同期妇科收治的非子宫内膜异位症良性卵巢囊肿51例为对照组,分别检测两组患者的血清CA125水平并比较.结果 观察组术前的血清CA125水平为(95.29 ±55.47) U/ml,明显高于对照组的(17.96 ±6.82) U/ml(P <0.05).观察组患者子宫内膜异位症临床病理分期Ⅱ-Ⅳ期的患者血清CA125的水平明显高于Ⅰ期的患者(P<0.05).观察组子宫内膜异位症临床病理分期和术前血清CA125水平呈正相关关系(r=0.8795,P<0.05).痛经评分1分、2分、3分的患者,其术前血清CA125水平明显高于痛经评分0分的患者(P<0.05).观察组痛经评分与其术前血清CA125水平呈正相关关系(r =0.5594,P<0.05).结论 检测CA125水平对卵巢子宫内膜异位症的诊断、治疗方案的制定以及病情预后的判断有重要的参考价值.

关 键 词:子宫内膜异位症  CA-125抗原

The clinical value of CA125 detection in ovarian endometriosis cyst
Zhang Junjiao , Zhou Panmei. The clinical value of CA125 detection in ovarian endometriosis cyst[J]. Chinese Journal of Primary Medicine and Pharmacy, 2013, 20(20): 3109-3111
Authors:Zhang Junjiao    Zhou Panmei
Affiliation:. Department of Obstetrics and Gynecology, the First People's Hospital of Wuyi County, Zhejiang 321200, China
Abstract:Objective To explore the application value of CA125 detection in the diagnosis and treatment of ovarian endometriosis cyst, to provide a reference for clinical diagnosis and treatment. Methods 51 patients with ovarian endometriosis cyst were selected as the observation group, and 51 patients with non endometriosis of benign ovarian cyst were selected as control group. The serum CA125 level was detected and compared between the two growps. Results Before operation, the serum CA125 level of the observation group was ( 95.29 ± 55.47 ) U/ml, which was significantly higher than that of the control group ( 17.96±6.82 ) U/ml ( P 〈 0.05 ). In the observation group ,serum CA125 level of patients with endometriosis clinical pathological stage II-IV was significantly higher than that of patients with stage I ( P 〈 0.05 ). The endometriosis clinical TNM stage was positively correlated with preoperative serum CA125 level in the observation group ( r = 0. 8795, P 〈 0.05 ). The preoperative serum CA125 level in patients with dysmenorrhea score 1 point ,2 points ,3 points was significantly higher than that in patients with dysmenorrhea score 0 point ( P 〈 0.05 ). The preoperative serum level of CA125 was positively correlated with dysmenorrhea score in the observation group ( r = 0. 5594, P 〈 0.05 ). Conclusion The detection of serum carbohydrate antigen CA125 level has important value in diagnosis, treatment and prognosis of ovarian endometriosis.
Keywords:Endometriosis  CA-125 antigen
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