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脑梗死患者进行治疗前后血浆Hcy、ET和NPY联检的临床意义
引用本文:王军,傅雷,施洪超,武捷,姜建东. 脑梗死患者进行治疗前后血浆Hcy、ET和NPY联检的临床意义[J]. 放射免疫学杂志, 2006, 19(4): 259-260
作者姓名:王军  傅雷  施洪超  武捷  姜建东
作者单位:南京医科大学附属南京第一医院神经科,210006;南京医科大学附属南京第一医院神经科,210006;南京医科大学附属南京第一医院神经科,210006;南京医科大学附属南京第一医院神经科,210006;南京医科大学附属南京第一医院神经科,210006
摘    要:目的:探讨了脑梗死患者治疗前后血浆同型半胱氨酸(Hcy)、内皮素(ET)和神经肽Y(NPY)水平的变化。方法:应用ELISA测定39例脑梗死患者血浆Hcy和放免法测定ET和NPY水平,并与35名正常健康人作比较。结果:脑梗死患者在治疗前血浆Hcy、ET、NPY水平非常显著地高于正常人组(P〈0.01),治疗后3个月仍高于正常人组水平(P〈0.05)。结论:测定脑梗死患者血浆Hcy、ET、NPY水平对观察病情和预后判定具有重要的临床价值。

关 键 词:脑梗死  同型半胱氨酸  内皮素  神经肽Y
收稿时间:2006-05-21
修稿时间:2006-05-21

Clinical Significance of Changes of Plasma Hcy, ET and NPY Levels After Treatment in Patients with Cerebral Infarction
Wang Jun, Fu Lei, Shi Hongchao,et al.. Clinical Significance of Changes of Plasma Hcy, ET and NPY Levels After Treatment in Patients with Cerebral Infarction[J]. Journal of Radioimmanology, 2006, 19(4): 259-260
Authors:Wang Jun   Fu Lei   Shi Hongchao  et al.
Abstract:Objective To investigate the changes of plasma Hcy,ET and NPY levels in patients with cerebral infarction.Methods Plasma Hcy(with ELISA) were determined ET and NPY(with RIA) levels in 39 patients with cerebral infarction both at admission and 35 controls.Results Before treatment,the plasma Hcy,ET and NPY levels were significantly higher in the patients than those in controls(P<0.01).After treatment,the plasma Hcy,ET and NPY levels remained significantly higher(P<0.05).Conclusion Changes of plasma Hcy ET and NPY contents after treatment might be of prognostic importance in patients with cerebral infarction.
Keywords:cerebral infarction  hemocysteine(Hcy)   endothelin(ET)  neuropeptide Y(NPY)
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