强化中性戊二醛与亚硝酸钠混合溶液消毒作用的观察

<正> 1983年,我站与上海医药工业研究院协作研制成一种合成工艺简单,既具硷性戊二醛杀菌作用又相对稳定的强化中性戊二醛。在试用中发现,它对碳钢制品有一定腐蚀作用,从而使应用范围受到限制。本文在上述中性戊二醛内加入0.5%亚硝酸钠防锈,并经实验室试验与现场试用以探讨其可行性。

OBSERVATION ON THE DISINFECTION EFFECT OF THE MIXTURE OF NEUTRAL GLUTARALDEHYDE AND SODIUM NITRITE

In order to reduce the corrosive effect of glutaraldehyde on metals, sodium nitrite was added as anticorrosive. It was showed in laboratory that 2% neutral glutaraldehyde with 0.5% sodium nitrite could kill completely the spores of Bacillus subtilis var. niger after 3 hr of contact, while neutral glutaraldehyde alone required 6 hr of contact to achieve the same results. This means that the sporicidal efficacy of the former is two times higher than that of the latter. With regard to the killing effect on Pseudomonas aeruginosa or inactivation effect on HBsAg, no difference was found whether sodium nitrite was added to glutaraldehyde or not. After addition of 0.5% sodium nitrite, the 2% neutral glutaraldehyde can keep effective for four weeks. No corrosion was found on metal medical instruments immersed in the mixture for several hours.