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| 微载体药物递送系统在姜黄素中的应用研究进展 | |
| 引用本文： | 陈进,代文婷,邢海燕,陈卫东. 微载体药物递送系统在姜黄素中的应用研究进展[J]. 中国现代应用药学, 2012, 29(10): 885-889 |
| 作者姓名： | 陈进 代文婷 邢海燕 陈卫东 |
| 作者单位： | 合肥市第二人民医院药学部，合肥 230011;合肥市第二人民医院药学部，合肥 230011;合肥市第二人民医院药学部，合肥 230011;安徽中医学院药学院，合肥 230031 |
| 基金项目： | 合肥市2010年度第一批科技计划（卫生类）项目合科[2011]25号 |
| 摘 要： | 目的综述微载体药物递送系统在姜黄素中的应用研究进展,进一步了解姜黄素的研究概况。方法分别介绍姜黄素的纳米粒、微球、微乳、微囊、胶束、脂质体、磷脂复合物、环糊精包合物等递送系统的研究进展。结果微载体药物递送系统被广泛的应用于提高姜黄素的溶解度和稳定性,进而提高药物在体内的生物利用度。结论微载体药物递送系统在姜黄素中的应用研究为姜黄素进一步应用于临床提供研究基础。 |
| 关 键 词： | 姜黄素 微载体药物递送系统 应用研究进展 |
| 收稿时间： | 2012-02-05 |
| 修稿时间： | 2012-05-10 |
Research Progress of Microcarrier Drug Delivery System for Curcumin |
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| CHEN Jin,DAI Wenting,XING Haiyan and CHEN Weidong. Research Progress of Microcarrier Drug Delivery System for Curcumin[J]. The Chinese Journal of Modern Applied Pharmacy, 2012, 29(10): 885-889 | |
| Authors: | CHEN Jin DAI Wenting XING Haiyan CHEN Weidong |
| Affiliation: | 1.Department of Pharmacy, the SeeondPeople＇s Hospital of Hefei, Hefei 230011, China 2. College of Pharmacy, the Traditional Chinese Medicine College of Anhui, Hefei 230031, China) |
| Abstract: | OBJECTIVE To review research progress of microcarrier drug delivery system for curcumin to investigate more about the research situation of curcumin. METHODS Introduce the research progress of microcarrier drug delivery system for curcumin form of nanoparticles, microspheres, microemulsions, microcapsules, micelles, liposomes, phospholipid complexes, cyclodextrin inclusion compound respectively. RESULTS Microcarrier drug delivery system was widely used to improve the solubility and stability of curcumin, thus improving drug bioavailability in vivo. CONCLUSION The microcarrier drug delivery system has broad prospects, which can be applied in clinical application for curcumin. |
| Keywords: | curcumin microcarrier drug delivery system research progress |
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