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评价辨证论治疗效的分层多中心前瞻性队列研究方法
引用本文:胡立胜,郑淑美,王伟,李友林.评价辨证论治疗效的分层多中心前瞻性队列研究方法[J].中华中医药杂志,2008,23(2):146-148.
作者姓名:胡立胜  郑淑美  王伟  李友林
作者单位:北京中医药大学 北京100029(胡立胜,郑淑美,王伟),中日友好医院 北京100029(李友林)
基金项目:“973”国家重点基础研究发展计划资助(No.2006CB504603)
摘    要:辨证论治是中医诊治疾病的特色,是一个复杂干预的过程,如何评价辨证论治的临床疗效是需要解决的重要问题。随机对照试验是临床试验的金方案,但其实施条件严格,临床依从性低。队列研究临床可操作性高,但其控制偏倚差。分层多中心前瞻性队列研究,可以避免随机对照试验的实施困难和队列研究控制偏倚差的缺点,可作为中医辨证论治临床疗效评价的一种探索性方法。

关 键 词:分层多中心前瞻性队列研究  辨证论治  临床疗效评价
收稿时间:2007-07-05
修稿时间:2007年7月5日

The design of stratified, polycentric and prospective cohort study to appraise the curative efficacy of treatment based on syndrome differentiation
HU Li-sheng,ZHENG Shu-mei,WANG Wei,LI You-lin.The design of stratified, polycentric and prospective cohort study to appraise the curative efficacy of treatment based on syndrome differentiation[J].China Journal of Traditional Chinese Medicine and Pharmacy,2008,23(2):146-148.
Authors:HU Li-sheng  ZHENG Shu-mei  WANG Wei  LI You-lin
Abstract:Treatment based on syndrome differentiation which is a complicated procession,is a characteristic of Chinese medical diagnosis and treatment.How to appraise the efficacy of treatment based on syndrome differentiation becomes a important question.Randomized controlled trial is called golden design of clinical trial,but it has a strict condition and a low compliance.Cohort study has a high clinical operation,but it is difficult to control bias.Stratified,polycentric and prospective cohort study can avoid the shortcomings of randomized controlled trial and cohort study.So,it can be a prospective design to appraise the curative efficacy of treatment based on syndrome differentiation.
Keywords:Stratified and polycentric prospective cohort study  Treatment based on syndrome differentiation  Appraisement of clinical efficacy
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