精索静脉曲张与男性不育

精索静脉曲张(VC)是导致男性不育的最常见原因之一,手术是治疗VC的主要方法。近来,关于VC导致不育的病理机制研究较多,尤其是细胞分子机制的研究进展较快,主要包括生精细胞凋亡异常和氧化应激。同时,对于VC手术指征和各种术式优劣性的认识也渐趋统一。本文介绍VC导致不育的细胞分子机制及临床治疗决策的研究进展。

Varicocele and male infertility

Varicocele is a most common and surgically correctable cause of male infertility,for which varicocelectomy is the major treatment.Recent years have witnessed a lot of efforts devoted to the pathomechanism of varicocele-induced male infertility and rapid progress in researches on its cellular and molecular mechanisms,mainly including apoptotic abnormality and oxidative stress of germ cells.Meanwhile,researchers are coming to a consensus on the indications of vericocelectomy as well as the advantages and disa...