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| 孕妇与新生儿凝血酶原前体蛋白水平及相互关系的研究 | |
| 引用本文： | 杨善浦,董虹,吴月超,李素琴,龚爱敏,罗春林,吴叶健,陈松德.孕妇与新生儿凝血酶原前体蛋白水平及相互关系的研究[J].浙江医学,2008,30(5):442-444. |
| 作者姓名： | 杨善浦 董虹 吴月超 李素琴 龚爱敏 罗春林 吴叶健 陈松德 |
| 作者单位： | 1. 玉环县人民医院儿科,317600 2. 玉环县人民医院检验科,317600 3. 玉环县人民医院妇产科,317600 |
| 摘 要： | 目的探讨孕妇与新生儿脐血凝血酶原前体蛋白（PIVKA—ll）水平及其相互关系。方法采集在本院住院待产的74名健康孕妇静脉血及其新生儿脐血，用双抗夹心ELISA法测定孕妇静脉血及新生儿脐血PIVKA—ll水平，〉2ng／ml为PIVKA—ll阳性。结果74名孕妇PIVKA—ll阳性仅1例，阳性率为1．4％。74名孕妇分娩的新生儿（每一对双胞胎按1例计）脐血标本中，PIVKA—ll阳性33例，阳性率为44．6％，其中足月单胎新生儿占31例。仅1例PIVKA—ll阳性孕妇其新生儿脐血PIVKA—ll为阴性，33例脐血PIVKA—ll阳性的新生JL-8亲PIVKA—ll均为阴性。结论新生儿普遍存在亚临床维生素K（Vit K）缺乏现象，而且不能以孕妇PIVKA—ll水平推断新生儿实际的VitK营养状况。． |
| 关 键 词： | 凝血酶原前体蛋白 维生素K缺乏 孕妇 新生儿 孕妇分娩 新生儿 凝血酶原 蛋白水平 相互关系 研究 Levels vitamin K induced pregnant women relationship 营养状况 平推 现象 亚临床维生素 存在 母亲 阴性 单胎 足月 |
| 修稿时间： | 2007年12月12 |
Levels of(protein-Ⅱ induced by vitamin K absence,PIVKA-Ⅱ)in newborns and its relationship with their pregnant women |
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| YANG Shanpu,DONG Hong,WU Yuechao,et al..Levels of(protein-Ⅱ induced by vitamin K absence,PIVKA-Ⅱ)in newborns and its relationship with their pregnant women[J].Zhejiang Medical Journal,2008,30(5):442-444. | |
| Authors: | YANG Shanpu DONG Hong WU Yuechao |
| Institution: | YANG Shanpu,DONG Hong,WU Yuechao,et al. Yuhuan County People\'s Hospital,Taizhou 317600,China |
| Abstract: | Objective To investigate the levels of protein-II induced by vitamin K absence (PIVKA-II) in umbilical cord blood and related pregnant women. Methods PIVKA-II levels of 74 healthy pregnant women and their newborns was measured by enzyme-linked immunesorbent assay (ELISA). PIKVA-II 2ng/ml was set as cut-off level. Results Only one out of 74 pregnant women showed positive serum PIVKA-II with a positive rate of 1.4% (1/74), however, the newborn of this positive case had negative PIVKA-II in umbilical cord bloo... |
| Keywords: | PIVKA-II Vitamin K deficiency Pregnant women Newborns |
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