辨证分型联合西药治疗特发性血小板减少性紫癜随机平行对照研究 |
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引用本文: | 薛茜,;姜智慧. 辨证分型联合西药治疗特发性血小板减少性紫癜随机平行对照研究[J]. 实用中医内科杂志, 2014, 0(6): 85-87 |
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作者姓名: | 薛茜, 姜智慧 |
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作者单位: | [1]辽宁中医药大学:2012级血液病学方向硕士研究生,沈阳110032; [2]辽宁中医药大学:附属医院西医诊断教研室,沈阳110032 |
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摘 要: | [目的]观察辨证分型联合西药治疗特发性血小板减少性紫癜疗效。[方法]使用随机平行对照方法,将58例住院及门诊患者按抽签方法随机分为两组,常规补钙、保护胃黏膜、止血等对症治疗。对照组22例强的松,1mg/(kg·d),晨起顿服,血小板达到正常值后逐渐减量。治疗组36例血热妄行,清热凉血-活血止血;阴虚火旺,滋阴降火-凉血宁络;气虚不摄,健脾益气-养血摄血;瘀阻血络,化瘀通络-活血止血;西药治疗同对照组。连续治疗60d为1疗程。观测临床症状、血小板、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效8例,有效10例,好转14例,无效4例,总有效率88.80%。对照组显效3例,有效5例,好转8例,无效8例,总有效率63.60%。治疗组疗效优于对照组(P0.05)。[结论]辨证分型联合西药治疗特发性血小板减少性紫癜,疗效满意,无副作用,值得推广。
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关 键 词: | 特发性血小板减少性紫癜 血证 辨证分型 血热妄行 阴虚火旺 气虚不摄 瘀阻血络 强的松 血小板 中西医结合治疗 随机平行对照研究 |
Syndrome Differentiation Type Combined Prednisone Treatment of Idiopathic Thrombocytopenic Purpura Random Parallel Control Study |
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Affiliation: | XUE Qian, JIANG Zhihui ( Liaoning University of Traditional Chinese Medicine : a. Level 2012 Graduate Student, b.Affiliated, Shenyang 110032, China) |
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Abstract: | [ Objective ] To observe Syndrome differentiation type combined Prednisone curative effect in the treatment of idiopathic thrombocytopenic purpura. [ Methods ] Using random parallel control method, the method of 58 patients with inpatient and outpatient according to draw randomly divided into two groups, Two groups of both filling calcium, protection of gastric mucosa, hemostatic treatment.The control group of 22 cases of prednisone, 1 mg/ ( kg ~ d ), a morning suit, platelet after reaching normal gradually reduced.Blood-heat treated by clearing heat and cooling blood, the blood circulation hematischesis;fire excess from yin deficiency to nourish Yin and falling fire, Cold blood ning collaterals ; Qi deficiency is not taken to strengthening spleenand replenishing Qi, nourishing blood ejection;obstruction of collaterals by blood stasis, Blood stasis resistance, with stasis-reducing and venation-flowing, invigorating the circulation of the bleeding;Western medicine treatment with the control group. Continuous treatment of 60 to 1 course of treatment. Observation of clinical symptoms, platelet, adverse reactions. As a course treatment, judge curative effect. [ Result] The treatment group 8 cases had marked effect, 10 eases were effective, improvement in 14 cases, 4 cases were ineffective, the total effective rate was 88.80%. Control group 3 cases were markedly effective, effective in 5 cases, improvement in 8 cases, 8 no effect, the total effective rate was 63.60%. The treatment group curative effect is better than that of control group ( P〈O.05 ) . [ Conclusion] Combined Prednisone treatment of idiopathic thrornbocytopenic purpura, curative effect is satisfied, no side effect, is worth promoting. |
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Keywords: | Idiopathic thrombocytopenic purpura Syndrome differentiation type Prednisone Platelets Combine traditional Chinese and western medicine treatment Random parallel control study |
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