Association between gene polymorphisms of vitamin D receptor and pulmonary tuberculosis susceptibility:a meta-analysis |
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Authors: | Su Qian Ma Xiangyu Lin Hui Li Ying Hu Daiyu Xiong Hongyan Xu Rufu Li Yafei |
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Affiliation: | Su Qian1,2,Ma Xiangyu1,Lin Hui1*,Li Ying3,Hu Daiyu2,Xiong Hongyan1,Xu Rufu1,Li Yafei1 1Department of Epidemiology,College of Military Preventive Medicine,Third Military Medical University,Chongqing 400038,China 2Institute of Tuberculosis Prevention and Treatment of Chongqing,Chongqing 400050,China 3Department of Social Medicine and Health Service Management,Chongqing,400038,China |
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Abstract: | Background:The vitamin D receptor(VDR) gene is a primary candidate gene for tuberculosis susceptibility,but results of previous studies are somewhat contradictory and underpowered.Thus,it is essential to further explore the association between VDR gene polymorphisms and risk of pulmonary tuberculosis(PTB).Methods:A systematic review and meta-analysis about the association between FokI,TaqI,ApaI and BsmI polymorphisms and PTB susceptibility was conducted.Statistical Package for Social Science(Version 13.0) a... |
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Keywords: | Vitamin D receptor Pulmonary tuberculosis Polymorphism Meta-analysis |
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