| 浅论非洛地平的药理作用及临床应用 |
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| 引用本文： | 刘杰,朱杰华. 浅论非洛地平的药理作用及临床应用[J]. 中国医药指南, 2010, 8(19): 214-215 |
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| 作者姓名： | 刘杰 朱杰华 |
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| 作者单位： | 1. 深圳市龙岗区葵涌人民医院药剂科,518119
2. 深圳市龙岗区大鹏人民医院,518120 |
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| 摘 要： | 目的观察钙离子拮抗剂非洛地平的药理作用及治疗肾性高血压临床效果。方法选取148例肾性高血压患者均采用口服非洛地平片,2.5mg/次,2次/d,疗程为2个月。治疗后观察患者的血压、血、尿蛋白(β2-MG)、肾功能(BUN、Scr、UA、Ccr、24h尿蛋白定量)、不良反应及服药情况等。结果 148例患者在经过非洛地平治疗后收缩压、舒张压、血肌酐、尿素氮、肌酐清除率、血尿酸、24h尿蛋白定量比较差异均有统计学意义(P<0.05)。结论非洛地平对治疗肾性高血压有良好的效果。
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| 关 键 词： | 非洛地平 药理作用 肾性高血压 |
On the Pharmacological Effects of Felodipine and Its Clinical Application |
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| LIU Jie,HUANG Jian. On the Pharmacological Effects of Felodipine and Its Clinical Application[J]. Guide of China Medicine, 2010, 8(19): 214-215 |
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| Authors: | LIU Jie HUANG Jian |
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| Affiliation: | LIU Jie, HUANG Jian (1 Department of Pharmacy, Longgang District Kuiyong People＇s Hospital, Shenzhen 518119, China; 2 Dapeng People＇s Hospital of Longgang District, Shenzhen 518120, China) |
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| Abstract: | Objective To observe the calcium antagonist felodipine pharmacological effects and clinical effects of treating hypertension. Method Select 148 cases of renal hypertension patients with oral felodipine tablet, 2.5mg/times, 2 times a day regimen for 2 months. Observed after treatment of blood pressure, blood, urine protein （β2-MG）, renal function （BUN, Scr, UA, Ccr, 24-hour urine protein）, side effects and medication compliance. Results 148 patients after felodipine treatment systolic blood pressure, diastolic blood pressure, serum creatinine, urea nitrogen, creatinine clearance, uric acid, 24-hour urinary protein was significant difference （P〈0.05）. Conclusion Felodipine on renal hypertension was good results. |
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| Keywords: | Felodipine Pharmacology Renal hypertension |
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