瘢痕疙瘩术后电子线放射治疗48例

目的　探讨电子线放射治疗术后瘢痕疙瘩的效果。方法　随访 1994～ 2 0 0 2年间 4 8例(6 5处 )术后瘢痕疙瘩接受电子线放射治疗的患者 ,总照射剂量 2 5Gy ,随访时间均在 18个月以上 ,对治疗结果进行统计学分析和评估。结果　疗效分析表明 ,总复发率为 2 6 1% ,由感染所致瘢痕疙瘩和有家族史的患者复发率偏高 ,分别为 4 7 8%和 5 3 3% (P <0 0 5 )。患者的年龄、性别、病灶大小及解剖位置分布与复发率高低无直接关系。结论　术后电子线放射治疗对于防治瘢痕疙瘩的复发效果较好 ,是一种治疗瘢痕疙瘩安全有效的方法。

Postoperative electron beam irradiation therapy for keloid:a follow-up study of 48 patients

Objective To explore the effectiveness of postoperative electron beam irradiation therapy for keloid. Methods Forty-eight patients with 65 keloid sites were treated by surgical removal and postoperative 25 Gy electron beam irradiation from 1994 to 2002 and followed for over eighteen months. Statistical analysis was performed and therapeutic outcome was evaluated. Results The overall recurrence rate was 26%. Higher post-treatment recurrence rates were noted with keloid forming at infected sites and in patients with family history (47.8% and 53.3%) ( P <0.05). Meanwhile,patient age,sex,keloid size and location had no increased likehood of recurrence rate. Conclusion The study shows that postoperative electron beam irradiation therapy is a kind of safe and effective method in inhibiting recurrence of keloid formation and eradicating it.