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Performance characteristics of screening strategies to identify Lynch syndrome in women with ovarian cancer |
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| Authors: | Soyoun Rachel Kim MD Alicia Tone PhD Raymond H. Kim MD PhD Matthew Cesari MD Blaise A. Clarke MD Lua Eiriksson MD Tae Hart PhD Melyssa Aronson MS Spring Holter MS Alice Lytwyn MD Manjula Maganti MSc Leslie Oldfield MSc Steven Gallinger MD Marcus Q. Bernardini MD Amit M. Oza MD Bojana Djordjevic MD Jordan Lerner-Ellis PhD Emily Van de Laar MSc Danielle Vicus MD Trevor J. Pugh PhD Aaron Pollett MD Sarah E. Ferguson MD |
| Affiliation: | 1. Division of Gynecologic Oncology, Princess Margaret Cancer Centre, University Health Network, Sinai Health Systems, Toronto, Ontario, Canada;2. Fred A. Litwin Family Centre for Genetic Medicine, University Health Network, Toronto, Ontario, Canada Zane Cohen Centre for Digestive Diseases, Familial Gastrointestinal Cancer Registry, Mount Sinai Hospital, Toronto, Ontario, Canada Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Sinai Health Systems, Toronto, Ontario, Canada;3. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada;4. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, Canada;5. Zane Cohen Centre for Digestive Diseases, Familial Gastrointestinal Cancer Registry, Mount Sinai Hospital, Toronto, Ontario, Canada;6. Division of Anatomical Pathology, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada;7. Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada;8. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada;9. Division of General Surgery, Princess Margaret Cancer Centre, University Health Network, Sinai Health Systems, Toronto, Ontario, Canada;10. Division of Gynecologic Oncology, Princess Margaret Cancer Centre, University Health Network, Sinai Health Systems, Toronto, Ontario, Canada Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada;11. Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Sinai Health Systems, Toronto, Ontario, Canada;12. Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada;13. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada Ontario Institute for Cancer Research, University Health Network, Toronto, Ontario, Canada Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada;14. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada |
| Abstract: | |
| Keywords: | Lynch syndrome ovarian cancer screening tumor testing |