半乳糖凝集素3在急性缺血性脑卒中预后评估中的价值

目的：研究半乳糖凝集素3对急性缺血性脑卒中患者预后评估的价值。方法选取165例急性缺血性脑卒中患者，追踪随访观察12个月，记录复发脑卒中事件的情况，并检测其血清半乳糖凝集素3的浓度。结果至随访截止，165例急性缺血性脑卒中患者中共有65例患者在12个月内再次发生脑卒中事件，复发率为39．39％。复发脑卒中患者的血清半乳糖凝集素3水平显著高于无复发的患者，差异有统计学意义（P ＜0．05）。半乳糖凝集素3高水平患者复发脑卒中的比例显著高于低水平患者，差异有统计学意义（P ＜0．05）。结论半乳糖凝集素3是预测急性缺血性脑卒中患者预后的良好指标，该指标的检测有助于对患者进行复发危险评估。

The prognosis value of galectin-3 in patients with acute ischemic stroke~

Objective To evaluate the prognosis value of the expression of galectin 3 in patients with acute ischemic stroke. Methods 165 Patients with acute ischemic stroke had been observated for 12 months and their occurrence of recurrent stroke events were recorded. The concentration of galectin-3 was detected. Results 65 patients had recurrence stroke events with a rate of 39.39% within 12 months. It was also found that the serum concentration of galectin-3 in acute ischemic stroke recurrence patients were significantly higher than those of patients without recurrence, the difference was statistically significant（P〈0.05）. The rate of acute ischernic stroke recurrence in patients with high concentrations of galectin-3 was higher than that in patients with low concentrations of galectin-3, the difference was statistically significant（P〈0.05）. Conclusion Galectin-3 is a good indicator to predict the prognosis of patients with acute ischemic stroke,and it could be used to evaluate the risk of recurrence in patients.