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Animal models of early life stress: Implications for understanding resilience
Authors:David M. Lyons  Karen J. Parker  Alan F. Schatzberg
Affiliation:Department of Psychiatry and Behavioral Sciences, Stanford University, 1201 Welch Rd, MSLS P104, Stanford, CA 94305
Abstract:
In the mid‐1950s, Levine and his colleagues reported that brief intermittent exposure to early life stress diminished indications of subsequent emotionality in rats. Here we review ongoing studies of a similar process in squirrel monkeys. Results from these animal models suggest that brief intermittent exposure to stress promotes the development of arousal regulation and resilience. Implications for programs designed to enhance resilience in human development are discussed. © 2010 Wiley Periodicals, Inc. Dev Psychobiol 52: 402–410, 2010.
Keywords:emotion regulation  cognitive control  prefrontal plasticity  HPA axis  curiosity  anxiety  cortisol  squirrel monkey
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