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Dextran Mass Ratio Controls Particle Drying Dynamics in a Thermally Stable Dry Powder Vaccine for Pulmonary Delivery |
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| Authors: | Manser Myla Morgan Blair A. Feng Xueya Rhem Rod G. Dolovich Myrna B. Xing Zhou Cranston Emily D. Thompson Michael R. |
| Affiliation: | 1.Department of Chemical Engineering, McMaster University, Hamilton, ON, L8S 4L7, Canada ;2.McMaster Immunology Research Centre and Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, L8S 4L7, Canada ;3.Firestone Research Aerosol Laboratory, St. Joseph’s Healthcare and Department of Medicine, McMaster University and Hamilton, Hamilton, ON, L8N 4A6, Canada ;4.Department of Wood Science, University of British Columbia, 2424 Main Mall, Vancouver, BC, V6T 1Z4, Canada ;5.Department of Chemical and Biological Engineering, University of British Columbia, 2360 East Mall, Vancouver, BC, V6T 1Z3, Canada ; |
| Abstract: | Pharmaceutical Research - Thermally stable, spray dried vaccines targeting respiratory diseases are promising candidates for pulmonary delivery, requiring careful excipient formulation to... |
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