食管癌肉瘤14例

依据食管癌肉瘤的临床，病理特点，探讨其可能的组织学来源。方法对１４例食管癌肉瘤病人的临床资料进行了回顾性研究。结果：食管癌肉瘤多为息肉样腔内生长，有细短蒂和食管壁相连，个别呈浸润生长。

Carclnosarcoma of the Esophagus(Report of 14 Cases)

Objective:To evaluate the clinical and pathological characteristics of esophageal carcinosarcoma.Method The clinical materials of 14 patients with carcinosarcoma were retrospectively sutdied.Result:Grossly most of the tumors were ploypoid in shape and protruded into the lumen of the esophagus with a short narrow pedicle.Microscopically the tumors were composed of both carcinomatous and sarcomatous elements.Usually the sarcomatous element formed the bulk of the lesion and the carcinomatous element located at the base of the pedicle with the feature of early squamous cell carcinoma.None of 14 cases was extraextension direct invasion observed.The lymph node metastasis rate was 21.4%.The resectability rate was 100%.The 1 year,3 year,5 year and 10 year survival rates were 87.5%,75%,58.3% and 37.5%,respectively.Conclusion:Esophageal carcinosarcoma is an independent entity with little invasiveness,low lymph node metastasis and good prognosis.Surgical resection is the first preferrable and main treatment.Both carcinomatous and sarcomatous elements may have their origins from the same pluripotent stem cell of esophageal mucosa.