带与不带血管周围神经移植的比较

目的：比较带与不带血管周围神经移植的再生情况及探讨其再生机理。方法：用ＳＤ雄性大鼠５０只，随机分组，６只为正常对照组，其余等分为Ａ组（带血管神经移植组）和Ｂ组（不带血管神经移植组）。两组均在移植后不同时间取材，进行光镜、电镜对比观察。结果：在移植后的前４周，Ａ、Ｂ两组组织形态学变化基本相似。从第６周开始，移植段神经纤维再生率、有髓神经纤维再生率、有髓神经纤维直径恢复率、神经纤维变性率，Ａ组均明显优于Ｂ组，并进行了差异程度比较。Ａ组结缔组织增生少，神经纤维再生好。发现Ｂ组神经束内有结缔组织包裹２～３条神经纤维呈小束，再生而又变性的神经纤维多。结论：带血管周围神经移植优于不带血管的周围神经移植。

EXPERIMENTAL COMPARISON OF VASCULARIZED AND NONVASCULARIZED NERVE GRAFTING

Objective:To compare the results of vascularized and nonvascularized nerve grafting in rat.Metbods:50 SD rats were randomly divided into three groups:control group,vascularized nerve grafts(group A)and nonvascularized nerve grafts(group B).Samples were taken at different time after-operation,and observed by microscope and electron-microscope. Results:The results showed that dur-ing the first four weeks after grafting the histomorphology in group A and B were similar.But from the sixth week,group A was superior to group B in the rate of regeneration of nerve fibers,the recovery rate of diameter of myelinated nerve fibers and the rate of degeneration nerve fibers and so on. The con- nective tissues in group A were less than those in group B. The nerve fibers regeneration of group A was better than group B. Conclusion:The nerve regeneration in vascularized nerve grafting is superior than nonvascularized nerve grafting.