物理抗菌喷雾敷料在口腔癌术创预防感染的研究

目的:研究口腔癌术创全身应用抗菌药物的同时,局部应用物理抗菌方法的临床治疗效果。方法:60例口腔癌患者,随机分为治疗组30例和对照组30例。治疗组,从手术当日开始,在口腔、口咽、鼻咽部以及颈部术创喷涂洁悠神物理抗菌喷雾敷料,剂量为0.1mL/次,每日3次,直到术创愈合。对照组,常规口腔护理、换药。观察两组术创外观、愈合等级和愈合时间,血常规、肝肾功能等血液学检测。结果:两组术创愈合等级无显著差异(P>0.05),术创愈合时间治疗组较对照组缩短(P<0.05)。60例均未出现不良反应,用药后血液学检测无显著差异(P>0.05)。结论:口腔癌术后创面局部使用物理抗菌雾敷料在预防感染的安全性和有效性综合指标方面有一定的优势。

Study on Infection Prevention after Oral Cancer Operation by Using JUC Physical Antimicrobial Spray Dressing.

Objective:To study the clinical therapeutic effect of local use of physical antimicrobial film after oral tumor operation,combined with systemic use of antibacterial drugs.Methods: 60 patients after oral tumor operation were selected.One half were treated with JUC and the others accepted traditional method.Treated group was adminjstered physical antimicrobial spray dressing on incisions of oral cavity,oral pharynx,nasal pharynx,and neck from the operative day.The dosage was 0.1ml/spray,three times a day until the healing of the incision.Control group was performed conventional nursing and dressing change.Incision appearance,healing grade and healing time,hematology examinations such as blood routine examination,liver and kidney functions were observed.Results: There was no significant difference in the healing grade in both groups(P>0.05).The healing time of incision was shortened in the treated group compared with the control group(P<0.05).There were no side effects in all 60 cases,and there were no significant differences by hematology examinations after medication(P>0.05).Conclusion : Local use of physical antimicrobial spray dressing on incisions following oral cancer operation has certain advantages such as the safety and effectiveness in preventing infection.