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| 牙本质磷蛋白诱导矿化作用的研究 | |
| 引用本文： | 骆松江,李玉晶,万领,宿颖. 牙本质磷蛋白诱导矿化作用的研究[J]. 中华口腔医学杂志, 2003, 38(1): 56-58,I004 |
| 作者姓名： | 骆松江 李玉晶 万领 宿颖 |
| 作者单位： | 100050,首都医科大学附属北京口腔医院口腔医学研究所 |
| 基金项目： | 北京市自然科学基金资助项目 ( 9752 0 0 8) |
| 摘 要： | 目的：探讨牙本质磷蛋白（dentin phosphoprotein,DPP)诱导矿化的作用。方法：在体外矿化系统中利用入DPP与EAH－Sepharose 4B凝胶颗粒结合进行诱导矿化实验，通过扫描电镜观察生成物的形貌变化，X线衍射及等离子发射光谱分析生成物的组分和结构。结果：结合有人DPP的凝胶颗粒表面有矿化物形成，该矿化物钙磷比约为1．33，其X线衍射结果与羟基磷灰石更为相似。结论：人DPP与一定的支持物紧密结合后具有诱导矿化的作用。 |
| 关 键 词： | 牙本质 磷蛋白 诱导矿化 研究 牙再矿化 |
The effect of dentin phosphoprotein on inducing mineralization |
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| LUO Song jiang,LI Yu jing,WAN Ling,SU Ying Beijing Institute of Dental Research,Beijing Hospital for Stomatology,Capital University of Medical Sciences,Beijing ,China. The effect of dentin phosphoprotein on inducing mineralization[J]. Chinese journal of stomatology, 2003, 38(1): 56-58,I004 | |
| Authors: | LUO Song jiang LI Yu jing WAN Ling SU Ying Beijing Institute of Dental Research Beijing Hospital for Stomatology Capital University of Medical Sciences Beijing China |
| Affiliation: | Beijing Institute of Dental Research, Beijing Hospital for Stomatology, Capital University of Medical Sciences, Beijing 100050, China. |
| Abstract: | Objective To investigate the effect of dentin phosphoprotein(DPP) in inducing dentinal mineralization Methods Human DPP was combined with EAH Sepharose 4B beads and its function of inducing mineralization was studied in mineralization system in vitro The mineral formed on the surface of the beads was analyzed by scanning electron microscopy (SEM) and the structure was analyzed by X ray diffraction and plasma emission spectrum Results There was mineral formed on the beads with combined DPP and the mineral was calcium phosphates whose ratio of calcium to phosphate was 1 33 The diffractogram of the formed mineral was more similar to hydroxyapatite than to other calcium phosphates Conclusion When tightly combined with certain support substance, human DPP can induce mineralization |
| Keywords: | Phosphoproteins Dentin Tooth remineralization |
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